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NCT03981952 · ClinicalTrials.gov registry record · Phase 1

Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine

A Phase 1 study of Risk Reduction, sponsored by University of Maryland, Baltimore.

Completed
Registry status
Phase 1
Development phase
96
Enrollment target
1
Study location

NCT03981952 is a Phase 1 study of Risk Reduction that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 96 participants, below the 3,691-participant average among 13 other Risk Reduction trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03981952, a Phase 1 study of Risk Reduction, has completed, sponsored by University of Maryland, Baltimore.

COMPLETED
Registry status
Phase 1
Development phase
96 participants
Enrollment target
1
Study location

Study Summary

This is a randomized, placebo-controlled dose-escalation study. The main purpose of this research is to test the safety and measure the immune response of the trivalent vaccine against invasive Salmonella disease. The vaccine will be tested over a range of doses.

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL Trivalent Invasive Salmonella Disease Vaccine (6.25 µg)
  • BIOLOGICAL Trivalent Invasive Salmonella Disease Vaccine (12 µg)
  • BIOLOGICAL Trivalent Invasive Salmonella Disease Vaccine (25 µg)
  • BIOLOGICAL Trivalent Invasive Salmonella Disease Vaccine (highest, well-tolerated dose among Cohorts A-C)

Study Locations (1)

Maryland

  • University of Maryland, Baltimore, Center for Vaccine Development and Global Health - Baltimore

Trial Details

FieldValue
Enrollment Target 96 participants
Start Date 2019-10-28
Est. Completion 2021-05-07
Phase Phase 1

Sponsor

University of Maryland, Baltimore

560 total trials

What the Registry Record Tells You About NCT03981952

The ClinicalTrials.gov registry entry for NCT03981952 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,691-participant average among 13 other Risk Reduction trials with a reported enrollment target (97% lower). The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Risk Reduction appearing as the primary indexed condition, and to 5 interventions - of which Placebo is the first listed.

NCT03981952 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT03981952 about?

NCT03981952 is a clinical study titled "Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine". This is a randomized, placebo-controlled dose-escalation study. The main purpose of this research is to test the safety and measure the immune response of the trivalent vaccine against invasive Salmonella disease. The vaccine will be tested over a range of doses.

What is the current status of trial NCT03981952?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 96 participants. The study started on 2019-10-28. Estimated completion is 2021-05-07.

What conditions does trial NCT03981952 study?

This clinical trial studies the following conditions: Risk Reduction.

What interventions are being tested in trial NCT03981952?

The interventions under investigation include: Placebo (OTHER), Trivalent Invasive Salmonella Disease Vaccine (6.25 µg) (BIOLOGICAL), Trivalent Invasive Salmonella Disease Vaccine (12 µg) (BIOLOGICAL), Trivalent Invasive Salmonella Disease Vaccine (25 µg) (BIOLOGICAL), Trivalent Invasive Salmonella Disease Vaccine (highest, well-tolerated dose among Cohorts A-C) (BIOLOGICAL).

Who is sponsoring clinical trial NCT03981952?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03981952 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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