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REM Sleep Behavior Disorder: early-phase trial registry
6 of 12 indexed REM Sleep Behavior Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,429 of 28,707 conditions by registered trial count.
12 US clinical trials · 6 currently recruiting · #1,429 of 28,707 conditions by registered trial count
REM Sleep Behavior Disorder: 12 US clinical trials tracked, 6 recruiting.
REM Sleep Behavior Disorder is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Cedars-Sinai Medical Center, running 3 of these trials.
Enrollment posture brief
Registry condition rem-sleep-behavior-disorder
OPEN 6 | RECR 50% | LATE 1 | EARLY 5 | RANK #1429 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
REM Sleep Behavior Disorder lists 6 open slots (50% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for REM Sleep Behavior Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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REM Sleep Behavior Disorder is recruiting above its size-band peers.
6 of 12 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates REM Sleep Behavior Disorder research.
Cedars-Sinai Medical Center accounts for 3 of 12 trials (25%). 9 distinct sponsors appear on at least one study for this condition label.
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Most REM Sleep Behavior Disorder trials plan to enrol fewer than 100 people.
Median target enrolment is 60 among the 12 trials that report a genuine target (sentinel values excluded). 9 of those (75%) plan for fewer than 100 participants.
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REM Sleep Behavior Disorder research is mostly interventional.
9 interventional and 3 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
12 total, page 1 of 1
Natural History Study of Synucleinopathies
NYU Langone Health
NCT01799915
North American Prodromal Synucleinopathy Consortium Stage 2
Washington University School of Medicine
NCT05826457
Intestinal Immunity in Neurologic Disease
Yale University
NCT06329453
Neuroplasticity in RBD
University of Minnesota
NCT05471960
Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder
University of Minnesota
NCT06467461
Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder
University of Utah
NCT06441864
Cardiac Changes in Early Parkinson's Disease: A Follow up Study
Cedars-Sinai Medical Center
NCT04218968
Terazosin Effect on Cardiac Changes in Early Parkinson's Disease
Cedars-Sinai Medical Center
NCT04386317
Terazosin and Parkinson's Disease Extension Study
Cedars-Sinai Medical Center
NCT05109364
Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)
Michele Tagliati, MD
NCT03775096
Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls
Weill Medical College of Cornell University
NCT03675282
Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate
Stanford University
NCT04006925
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 4 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on REM Sleep Behavior Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on REM Sleep Behavior Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this REM Sleep Behavior Disorder page
12 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 REM Sleep Behavior Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Cedars-Sinai Medical Center sponsors the most REM Sleep Behavior Disorder trials on record, review their full trial history before evaluating a specific study. See Cedars-Sinai Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This REM Sleep Behavior Disorder condition card totals 12 registered trials; most-linked intervention Carvedilol; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.