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2026 data Public-data reference. official source

Relapsed or Refractory Multiple Myeloma

Open-data reference.

10 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 810 participants

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Celgene

NCT05519085

RECRUITING Phase 1 180 participants

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

Janssen Research & Development

NCT05652335

RECRUITING Phase 1 166 participants

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

ModernaTX

NCT07116616

RECRUITING Phase 1 130 participants

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

Jiangsu Simcere Pharmaceutical Co.

NCT06375044

ACTIVE NOT RECRUITING Phase 3 864 participants

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Janssen Research & Development

NCT05455320

ACTIVE NOT RECRUITING Phase 3 614 participants

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT05572515

ACTIVE NOT RECRUITING Phase 3 525 participants

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)

Bristol-Myers Squibb

NCT05552976

ACTIVE NOT RECRUITING Phase 1 108 participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT06425991

COMPLETED Phase 1 11 participants

Cabozantinib (XL184) in Patients With Relapsed or Refractory Myeloma

Memorial Sloan Kettering Cancer Center

NCT01866293

COMPLETED Phase 1 10 participants

Study to Evaluate the Safety and Efficacy of Anti-CD38 CAR-T in Relapsed or Refractory Multiple Myeloma Patients

Sorrento Therapeutics

NCT03464916

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 3 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Relapsed or Refractory Multiple Myeloma Trial Landscape

ClinicalTrials.gov lists 10 US studies indexed under Relapsed or Refractory Multiple Myeloma, and 4 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Relapsed or Refractory Multiple Myeloma shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Relapsed or Refractory Multiple Myeloma is led by Janssen Research & Development with 4 indexed trials, alongside 6 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Relapsed or Refractory Multiple Myeloma?

PlainTrial tracks 10 US clinical trials for Relapsed or Refractory Multiple Myeloma, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Relapsed or Refractory Multiple Myeloma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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