Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Recurrent Neuroblastoma: early-phase trial registry

1 of 10 indexed Recurrent Neuroblastoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 1 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Recurrent Neuroblastoma: 10 US clinical trials tracked, 1 recruiting.

Recurrent Neuroblastoma is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

Enrollment posture brief

Registry condition recurrent-neuroblastoma

OPEN 1 | RECR 10% | LATE 0 | EARLY 8 | RANK #1724 | SPON 6

Nearest open-share peer: Angina Pectoris (10% recruiting · 10 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%Recurrent Neuroblastoma (thi…10%
Open-enrollment share among volume-matched conditions near Recurrent Neuroblastoma

Recurrent Neuroblastoma lists 1 open slots (10% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Neuroblastoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Neuroblastoma is recruiting below its size-band peers.

    1 of 10 indexed trials (10%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Neuroblastoma research.

    National Cancer Institute (NCI) accounts for 6 of 10 trials (60%). 3 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Neuroblastoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 94 among the 10 trials that report a genuine target (sentinel values excluded). 6 of those (60%) plan for fewer than 100 participants.

  4. Recurrent Neuroblastoma research is mostly interventional.

    8 interventional and 2 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 24

Open and recent trials

10 total, page 1 of 1

RECRUITING Phase 1 90 participants

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

St. Jude Children's Research Hospital

NCT04901702

ACTIVE NOT RECRUITING 376 participants

Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma

Children's Oncology Group

NCT03057626

ACTIVE NOT RECRUITING Phase 2 94 participants

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Children's Oncology Group

NCT03794349

ACTIVE NOT RECRUITING Phase 1 27 participants

Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma

National Cancer Institute (NCI)

NCT01711554

ACTIVE NOT RECRUITING Phase 2 3 participants

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT04195555

COMPLETED 9,350 participants

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

Children's Oncology Group

NCT00436696

COMPLETED Phase 1 140 participants

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

National Cancer Institute (NCI)

NCT02304458

COMPLETED Phase 2 100 participants

Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood

National Cancer Institute (NCI)

NCT00030667

COMPLETED Phase 2 73 participants

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

National Cancer Institute (NCI)

NCT01767194

COMPLETED Phase 1 6 participants

Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma

National Cancer Institute (NCI)

NCT00005576

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4

Named interventions

Most-linked intervention names on Recurrent Neuroblastoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
5 trials
Dinutuximab Biological
3 trials
Temozolomide Drug
3 trials
Pharmacological Study Other
2 trials
Sargramostim Biological
2 trials
Irinotecan Hydrochloride Drug
2 trials
isotretinoin Drug
1 trials
monoclonal antibody Ch14.18 Biological
1 trials

US sites by state

Facility locations filed on Recurrent Neuroblastoma trials. A trial with sites in several states counts in each.

California 9 trials
Colorado 6 trials
Arkansas 4 trials
Alabama 4 trials
Pennsylvania 3 trials
Georgia 3 trials
Delaware 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Neuroblastoma page

10 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Neuroblastoma condition card totals 10 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.