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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Recurrent Marginal Zone Lymphoma: early-phase trial registry

1 of 12 indexed Recurrent Marginal Zone Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 1 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Recurrent Marginal Zone Lymphoma: 12 US clinical trials tracked, 1 recruiting.

Recurrent Marginal Zone Lymphoma is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 2 of these trials.

Enrollment posture brief

Registry condition recurrent-marginal-zone-lymphoma

OPEN 1 | RECR 8% | LATE 0 | EARLY 12 | RANK #1429 | SPON 2

Nearest open-share peer: Allergic Rhinitis (8% recruiting · 24 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Recurrent Marginal Zone (th…8%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Recurrent Marginal Zone Lymphoma

Recurrent Marginal Zone Lymphoma lists 1 open slots (8% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Marginal Zone Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Marginal Zone Lymphoma is recruiting below its size-band peers.

    1 of 12 indexed trials (8.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Marginal Zone Lymphoma research.

    Mayo Clinic accounts for 2 of 12 trials (16.7%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Marginal Zone Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 28 among the 12 trials that report a genuine target (sentinel values excluded). 12 of those (100%) plan for fewer than 100 participants.

  4. Recurrent Marginal Zone Lymphoma research is mostly interventional.

    12 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 22

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 1 27 participants

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

Mayo Clinic

NCT06191887

ACTIVE NOT RECRUITING Phase 1 53 participants

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

Fred Hutchinson Cancer Center

NCT03277729

ACTIVE NOT RECRUITING Phase 1 48 participants

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

Kami Maddocks, MD

NCT01479842

ACTIVE NOT RECRUITING Phase 1 43 participants

Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma

Barbara Ann Karmanos Cancer Institute

NCT03147885

ACTIVE NOT RECRUITING Phase 1 39 participants

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

National Cancer Institute (NCI)

NCT01955499

ACTIVE NOT RECRUITING Phase 1 36 participants

Nivolumab and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

David Bond, MD

NCT03015896

ACTIVE NOT RECRUITING Phase 1 22 participants

Obinutuzumab, Venetoclax, and Lenalidomide in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Beth Christian

NCT02992522

ACTIVE NOT RECRUITING Phase 2 20 participants

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

University of Washington

NCT04205409

ACTIVE NOT RECRUITING Phase 1 18 participants

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT03479268

ACTIVE NOT RECRUITING Phase 1 4 participants

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Thomas Jefferson University

NCT04447716

COMPLETED Phase 2 28 participants

Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation

National Cancer Institute (NCI)

NCT00058305

COMPLETED Phase 1 11 participants

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

Mayo Clinic

NCT03035331

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 2

Named interventions

Most-linked intervention names on Recurrent Marginal Zone Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
4 trials
Lenalidomide Drug
3 trials
Ibrutinib Drug
2 trials
Nivolumab Biological
2 trials
Biospecimen Collection Procedure
2 trials
Venetoclax Drug
2 trials
vincristine sulfate Drug
1 trials
bryostatin 1 Drug
1 trials

US sites by state

Facility locations filed on Recurrent Marginal Zone Lymphoma trials. A trial with sites in several states counts in each.

Ohio 5 trials
Washington 2 trials
Georgia 2 trials
Pennsylvania 1 trials
New York 1 trials
Minnesota 1 trials
Michigan 1 trials
Illinois 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Marginal Zone Lymphoma page

12 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 1 Recurrent Marginal Zone Lymphoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Mayo Clinic sponsors the most Recurrent Marginal Zone Lymphoma trials on record, review their full trial history before evaluating a specific study. See Mayo Clinic's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Marginal Zone Lymphoma condition card totals 12 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.