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ClinicalTrials.gov 1 recruiting now official registry

Recurrent Marginal Zone Lymphoma clinical trials

1 of 12 indexed Recurrent Marginal Zone Lymphoma trials are currently recruiting.

12 US clinical trials · 1 currently recruiting

Recurrent Marginal Zone Lymphoma is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 2 of these trials.

The research picture

Recurrent Marginal Zone Lymphoma has 12 registered US clinical trials, 1 of them open to new participants right now, about 8% of the total.

1
recruiting participants now
8%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Mayo Clinic
Phase 110Phase 22

Active & Recent Trials

12 total, page 1 of 1

RECRUITING Phase 1 27 participants

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

Mayo Clinic

NCT06191887

ACTIVE NOT RECRUITING Phase 1 53 participants

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

Fred Hutchinson Cancer Center

NCT03277729

ACTIVE NOT RECRUITING Phase 1 48 participants

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

Kami Maddocks, MD

NCT01479842

ACTIVE NOT RECRUITING Phase 1 43 participants

Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma

Barbara Ann Karmanos Cancer Institute

NCT03147885

ACTIVE NOT RECRUITING Phase 1 39 participants

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

National Cancer Institute (NCI)

NCT01955499

ACTIVE NOT RECRUITING Phase 1 36 participants

Nivolumab and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

David Bond, MD

NCT03015896

ACTIVE NOT RECRUITING Phase 1 22 participants

Obinutuzumab, Venetoclax, and Lenalidomide in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Beth Christian

NCT02992522

ACTIVE NOT RECRUITING Phase 2 20 participants

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

University of Washington

NCT04205409

ACTIVE NOT RECRUITING Phase 1 18 participants

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT03479268

ACTIVE NOT RECRUITING Phase 1 4 participants

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Thomas Jefferson University

NCT04447716

COMPLETED Phase 2 28 participants

Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation

National Cancer Institute (NCI)

NCT00058305

COMPLETED Phase 1 11 participants

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

Mayo Clinic

NCT03035331

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Marginal Zone Lymphoma Trial Landscape

12 indexed Recurrent Marginal Zone Lymphoma studies · 1 recruiting (8%).

Phase mix: 0 late (III/IV) vs 12 early (I/II).

Top sponsor: Mayo Clinic (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Marginal Zone Lymphoma?

PlainTrial tracks 12 US clinical trials for Recurrent Marginal Zone Lymphoma, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Marginal Zone Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.