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ClinicalTrials.gov 4 recruiting now official registry

Pruritus clinical trials

4 of 13 indexed Pruritus trials are currently recruiting.

13 US clinical trials · 4 currently recruiting

Pruritus is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Asana BioSciences, running 1 of these trials.

The research picture

Pruritus has 13 registered US clinical trials, 4 of them open to new participants right now, about 31% of the total.

4
recruiting participants now
31%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
1
top sponsor: Asana BioSciences
Phase 12Phase 25Phase 32

Active & Recent Trials

13 total, page 1 of 1

RECRUITING Phase 3 284 participants

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

Sanofi

NCT05263206

RECRUITING NA 60 participants

The Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in Patients With Atopic Dermatitis

Nexgen Dermatologics

NCT06488742

RECRUITING NA 34 participants

VR-PMR for Post-Burn Symptoms

Johns Hopkins University

NCT07317271

RECRUITING NA 12 participants

Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic Itch

Mayo Clinic

NCT06751056

COMPLETED Phase 2 547 participants

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

AOBiome

NCT04490109

COMPLETED Phase 2 144 participants

A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatitis

Formation Bio

NCT05870865

COMPLETED Phase 2 62 participants

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Escient Pharmaceuticals

NCT05525520

COMPLETED Phase 2 62 participants

Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis

Trevi Therapeutics

NCT02174419

COMPLETED NA 53 participants

Study Determining Safety and Efficacy of Avena Sativa (Oat) Skincare Products for Treating Skin Dryness and Itching in Cancer Patients

Johnson & Johnson Consumer Inc. (J&JCI)

NCT03796052

COMPLETED Phase 1 24 participants

Study to Evaluate ASN008 Topical Gel (TG)

Asana BioSciences

NCT03798561

COMPLETED Early Phase 1 20 participants

Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli

Wright State University

NCT05287724

COMPLETED Phase 3 15 participants

Gabapentin to Treat Itch in Patients With Liver Disease

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00058890

COMPLETED Phase 2 14 participants

Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients

Jean Yuh Tang

NCT02654483

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pruritus Trial Landscape

13 indexed Pruritus studies · 4 recruiting (31%).

Phase mix: 2 late (III/IV) vs 7 early (I/II).

Top sponsor: Asana BioSciences (1 trial), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pruritus?

PlainTrial tracks 13 US clinical trials for Pruritus, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pruritus?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.