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NCT05287724 · ClinicalTrials.gov registry record · Early Phase 1
Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli
A Early Phase 1 study of Pruritus and Skin Disorder, sponsored by Wright State University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05287724 is a Early Phase 1 study of Pruritus and Skin Disorder that has completed, run by Wright State University. The registered enrollment target is 20 participants, below the 109-participant average among 12 other Pruritus trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05287724, a Early Phase 1 study of Pruritus and Skin Disorder, has completed, sponsored by Wright State University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this double-blinded placebo-controlled cross-over study is to define the role of the over the counter agent, N-acetyl cysteine (NAC), in mitigating the development of pruritus (skin itching). The study is designed to have all subjects treated with a seven-day regimen of both NAC and placebo. NAC will be prescribed at a dose of 1,500 mg twice daily for seven days. Subjects will initially be randomly assigned (1:1) to either the NAC or placebo arm of the study, before crossing over to the opposite arm after completing a minimum of 30-day washout period. The study will encompass a period of approximately 11 weeks (about 2 and a half months).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG N-acetyl cysteine
Study Locations (1)
Ohio
- Wright State Physicians - Fairborn
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-06-19 |
| Est. Completion | 2024-01-04 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05287724
The ClinicalTrials.gov registry entry for NCT05287724 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 109-participant average among 12 other Pruritus trials with a reported enrollment target (82% lower). The listed sponsor is Wright State University, which has 32 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Pruritus appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05287724 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT05287724 about?
NCT05287724 is a clinical study titled "Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli". The objective of this double-blinded placebo-controlled cross-over study is to define the role of the over the counter agent, N-acetyl cysteine (NAC), in mitigating the development of pruritus (skin itching). The study is designed to have all subjects treated with a seven-day regimen of both NAC and...
What is the current status of trial NCT05287724?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2022-06-19. Estimated completion is 2024-01-04.
What conditions does trial NCT05287724 study?
This clinical trial studies the following conditions: Pruritus, Skin Disorder.
What interventions are being tested in trial NCT05287724?
The interventions under investigation include: Placebo (DRUG), N-acetyl cysteine (DRUG).
Who is sponsoring clinical trial NCT05287724?
This trial is sponsored by Wright State University, which has 32 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05287724 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.