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ClinicalTrials.gov 31 recruiting now official registry

Prostate Carcinoma clinical trials

31 of 60 indexed Prostate Carcinoma trials are currently recruiting.

60 US clinical trials · 31 currently recruiting

Prostate Carcinoma is the subject of 60 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Jonsson Comprehensive Cancer Center, running 10 of these trials.

The research picture

Prostate Carcinoma has 60 registered US clinical trials, 31 of them open to new participants right now, about 52% of the total.

31
recruiting participants now
52%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
10
top sponsor: Jonsson Comprehensive Cancer Center
Phase 17Phase 215Phase 33

Active & Recent Trials

60 total, page 1 of 2

RECRUITING 675 participants

Investigation Into Detection of Prostate Cancer Using Voided Urine (Prostate VPAC)

Thomas Jefferson University

NCT04788277

RECRUITING NA 500 participants

Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement

Covenant Health Cancer Center

NCT06200259

RECRUITING 450 participants

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

University of Washington

NCT04472338

RECRUITING Phase 2 400 participants

EMBRACE: Exercising Together

OHSU Knight Cancer Institute

NCT06049355

RECRUITING 300 participants

Longitudinal Advanced Prostate Cancer Cohort (LAPCC)

University of Southern California

NCT06067295

RECRUITING 275 participants

Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification

Jonsson Comprehensive Cancer Center

NCT04765150

RECRUITING NA 250 participants

Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE

OHSU Knight Cancer Institute

NCT06011499

RECRUITING NA 250 participants

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men

Mayo Clinic

NCT06541210

RECRUITING NA 224 participants

Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

City of Hope Medical Center

NCT05519878

RECRUITING Phase 2 210 participants

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

City of Hope Medical Center

NCT05869682

RECRUITING Phase 2 200 participants

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

M.D. Anderson Cancer Center

NCT04947254

RECRUITING NA 147 participants

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Mayo Clinic

NCT06788886

RECRUITING NA 130 participants

MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial

University of Southern California

NCT07162194

RECRUITING Phase 3 108 participants

Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer

Mayo Clinic

NCT06625034

RECRUITING NA 100 participants

Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy

Roswell Park Cancer Institute

NCT04646434

RECRUITING NA 100 participants

MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer

Mayo Clinic

NCT05438563

RECRUITING Phase 2 90 participants

An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique

Emory University

NCT06865768

RECRUITING Phase 2 90 participants

Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)

Jonsson Comprehensive Cancer Center

NCT06216249

RECRUITING Phase 2 81 participants

An Investigational Scan (Flotufolastat F 18 PET/CT) for Detecting Residual or Recurrent Disease in Patients Who Completed Focal Therapy for Prostate Cancer.

Jonsson Comprehensive Cancer Center

NCT07185165

RECRUITING NA 80 participants

A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients

University of Michigan Rogel Cancer Center

NCT07291414

RECRUITING NA 72 participants

Community-Based Health Coach for Access to Germline Genetic Testing Among African American Men With Prostate Cancer

University of California, San Francisco

NCT04763980

RECRUITING 60 participants

Screening and Staging of Benign vs Malignant Pelvic Abnormalities

Mayo Clinic

NCT07407959

RECRUITING Phase 2 60 participants

Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

City of Hope Medical Center

NCT07202247

RECRUITING NA 60 participants

Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy

City of Hope Medical Center

NCT07218718

RECRUITING Phase 2 60 participants

Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy

Shehzad Basaria, M.D.

NCT06957691

RECRUITING 53 participants

iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men

Mayo Clinic

NCT06535802

RECRUITING Phase 2 48 participants

Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

University of California, San Francisco

NCT05766371

RECRUITING Early Phase 1 30 participants

99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT04857502

RECRUITING Early Phase 1 30 participants

Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial

Jonsson Comprehensive Cancer Center

NCT07164027

RECRUITING NA 20 participants

[18F]-rhPSMA PET-CT Imaging Performance in Patients With Prostate Cancer

City of Hope Medical Center

NCT06580015

RECRUITING NA 10 participants

Exploring the Potential of Robotic Telesurgery in Remote Settings

AdventHealth

NCT07130708

ACTIVE NOT RECRUITING NA 76,685 participants

Screening for Prostate Cancer in Older Patients (PLCO Screening Trial)

National Cancer Institute (NCI)

NCT00002540

ACTIVE NOT RECRUITING NA 2,500 participants

Long-Term Follow-Up in Patients With Prostate Cancer After Surgery

City of Hope Medical Center

NCT03035500

ACTIVE NOT RECRUITING NA 852 participants

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

ECOG-ACRIN Cancer Research Group

NCT03697148

ACTIVE NOT RECRUITING NA 465 participants

HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics

City of Hope Medical Center

NCT04905082

ACTIVE NOT RECRUITING Phase 2 360 participants

To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

ECOG-ACRIN Cancer Research Group

NCT04597359

ACTIVE NOT RECRUITING NA 261 participants

Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study

Fred Hutchinson Cancer Center

NCT04081779

ACTIVE NOT RECRUITING Phase 2 200 participants

Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer

M.D. Anderson Cancer Center

NCT03772834

ACTIVE NOT RECRUITING NA 168 participants

Evaluation of the Impact of Empty Versus Full Bladder in Patients With Prostate Cancer, RELIEF Trial

Mayo Clinic

NCT06037863

ACTIVE NOT RECRUITING 118 participants

Enhanced Genetic Awareness and Genetic Evaluation for Men Through Technology, ENGAGEMENT Study

Thomas Jefferson University

NCT04789018

ACTIVE NOT RECRUITING 98 participants

Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer

Mayo Clinic

NCT06326216

ACTIVE NOT RECRUITING NA 98 participants

Magnetic Resonance Whole Body Diffusion-Weighted Imaging in Finding Bone or Lymph Node Metastasis in Participants With High-Risk Prostate Cancer

M.D. Anderson Cancer Center

NCT03085043

ACTIVE NOT RECRUITING Phase 2 96 participants

Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC

M.D. Anderson Cancer Center

NCT03263650

ACTIVE NOT RECRUITING NA 86 participants

Micro-Ultrasound for the Detection and Localization of Prostate Cancer Tumors in Patients Undergoing Radical Prostatectomy

Jonsson Comprehensive Cancer Center

NCT04299620

ACTIVE NOT RECRUITING Phase 3 70 participants

Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)

Thomas Jefferson University

NCT05336786

ACTIVE NOT RECRUITING Early Phase 1 65 participants

An Investigational Scan (MRI With Dixon Based Sequences) in Detecting Prostate Cancer

M.D. Anderson Cancer Center

NCT05047965

ACTIVE NOT RECRUITING NA 34 participants

RefleXion PET/CT Imaging Performance in Patients With Prostate Cancer

City of Hope Medical Center

NCT05470699

ACTIVE NOT RECRUITING NA 33 participants

Novel Synthetic T2W MR Imaging and Spin Parameter Mapping Techniques for Screening Prostate Cancer

M.D. Anderson Cancer Center

NCT05055843

ACTIVE NOT RECRUITING Early Phase 1 30 participants

Image-Guided (68Ga-PSMA-11 PET/CT) Prostate Biopsy for the Diagnosis of Prostate Cancer in Men With Prior Negative/Inconclusive Biopsy

Jonsson Comprehensive Cancer Center

NCT05160597

ACTIVE NOT RECRUITING Phase 1 30 participants

Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation

Jonsson Comprehensive Cancer Center

NCT04457232

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 15
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Prostate Carcinoma Trial Landscape

60 indexed Prostate Carcinoma studies · 31 recruiting (52%).

Phase mix: 3 late (III/IV) vs 22 early (I/II).

Top sponsor: Jonsson Comprehensive Cancer Center (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Prostate Carcinoma?

PlainTrial tracks 60 US clinical trials for Prostate Carcinoma, of which 31 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.