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Primary Insomnia clinical trials
All 13 indexed Primary Insomnia trials have closed enrollment.
13 US clinical trials ·
Primary Insomnia is the subject of 13 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Rochester, running 3 of these trials.
The research picture
Primary Insomnia has 13 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.
- 0
- recruiting participants now
- 0%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 3
- top sponsor: University of Rochester
Active & Recent Trials
13 total, page 1 of 1
6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia
Sumitomo Pharma America
NCT00352144
Comparison of Two Temperatures to Treat Insomnia
Cereve
NCT01790256
The Role of Partial Reinforcement in the Long Term Management of Insomnia
University of Pennsylvania
NCT00662155
Behavioral Insomnia Therapy in Primary Care
US Department of Veterans Affairs
NCT00105872
Two Contrasting Interventions for Sleep Management
University of Utah
NCT01804036
A High Density EEG Comparison of Sleep Patterns in Insomnia
University of Wisconsin, Madison
NCT01960452
The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia
University of Rochester
NCT00124384
Metabolomics of Insomnia-Related Hyperarousal
University of Pennsylvania
NCT01957111
Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot Study
University of Minnesota
NCT00515177
The Psychoneuroimmunology of Insomnia
University of Rochester
NCT00680771
Testing the Nocturnal Sleep Latency Profile in Primary Insomnia
University of Pittsburgh
NCT00167375
A Pilot Study Of The Effects Of Microcurrent On Three Sleep Surveys
Logan College of Chiropractic
NCT00520832
Sleep Homeostasis in Primary Insomnia
University of Rochester
NCT00256503
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 3 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Primary Insomnia Trial Landscape
13 indexed Primary Insomnia studies · 0 recruiting (0%).
Phase mix: 2 late (III/IV) vs 3 early (I/II).
Top sponsor: University of Rochester (3 trials), 9 others listed. 13 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Primary Insomnia?
PlainTrial tracks 13 US clinical trials for Primary Insomnia, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Primary Insomnia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.