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ClinicalTrials.gov enrollment closed full pipeline small index

Primary Insomnia: full-pipeline trial registry

A small indexed set (13 trials) with no open enrollment listed right now.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · none currently recruiting · #1,315 of 28,707 conditions by registered trial count

Primary Insomnia: 13 US clinical trials tracked, none currently recruiting.

Primary Insomnia is the subject of 13 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Rochester, running 3 of these trials.

Enrollment posture brief

Registry condition primary-insomnia

OPEN 0 | RECR 0% | LATE 2 | EARLY 3 | RANK #1315 | SPON 3

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Primary Insomnia (this)0%
Open-enrollment share among volume-matched conditions near Primary Insomnia

Primary Insomnia has no open enrollment in this registry pull (13 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Primary Insomnia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Primary Insomnia is recruiting below its size-band peers.

    0 of 13 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Primary Insomnia research.

    University of Rochester accounts for 3 of 13 trials (23.1%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Primary Insomnia trials plan to enrol fewer than 100 people.

    Median target enrolment is 40 among the 13 trials that report a genuine target (sentinel values excluded). 9 of those (69.2%) plan for fewer than 100 participants.

  4. Primary Insomnia splits between interventional and observational designs.

    9 interventional and 4 observational studies make up this index (69.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 23Phase 31Phase 41

Indexed trials (enrollment closed)

13 total, page 1 of 1

COMPLETED Phase 3 830 participants

6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia

Sumitomo Pharma America

NCT00352144

COMPLETED NA 144 participants

Comparison of Two Temperatures to Treat Insomnia

Cereve

NCT01790256

COMPLETED NA 129 participants

The Role of Partial Reinforcement in the Long Term Management of Insomnia

University of Pennsylvania

NCT00662155

COMPLETED NA 100 participants

Behavioral Insomnia Therapy in Primary Care

US Department of Veterans Affairs

NCT00105872

COMPLETED Phase 2 72 participants

Two Contrasting Interventions for Sleep Management

University of Utah

NCT01804036

COMPLETED 45 participants

A High Density EEG Comparison of Sleep Patterns in Insomnia

University of Wisconsin, Madison

NCT01960452

COMPLETED Phase 4 40 participants

The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia

University of Rochester

NCT00124384

COMPLETED 32 participants

Metabolomics of Insomnia-Related Hyperarousal

University of Pennsylvania

NCT01957111

COMPLETED Phase 2 30 participants

Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot Study

University of Minnesota

NCT00515177

COMPLETED 28 participants

The Psychoneuroimmunology of Insomnia

University of Rochester

NCT00680771

COMPLETED 24 participants

Testing the Nocturnal Sleep Latency Profile in Primary Insomnia

University of Pittsburgh

NCT00167375

COMPLETED Phase 2 20 participants

A Pilot Study Of The Effects Of Microcurrent On Three Sleep Surveys

Logan College of Chiropractic

NCT00520832

COMPLETED NA 18 participants

Sleep Homeostasis in Primary Insomnia

University of Rochester

NCT00256503

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Primary Insomnia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Zolpidem Drug
2 trials
General cognitive/behavioral interventions for insomnia Behavioral
1 trials
eszopiclone 3 mg qHS Drug
1 trials
Microcurrent Device
1 trials
eszopiclone Drug
1 trials
Mind-Body Bridging Behavioral
1 trials
Serial awakenings Behavioral
1 trials
Cereve Sleep System at 14-16 degrees C Device
1 trials

US sites by state

Facility locations filed on Primary Insomnia trials. A trial with sites in several states counts in each.

Pennsylvania 3 trials
New York 3 trials
Missouri 2 trials
Florida 2 trials
Colorado 2 trials
Wisconsin 1 trials
Utah 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Primary Insomnia page

13 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Primary Insomnia trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • University of Rochester sponsors the most Primary Insomnia trials on record, review their full trial history before evaluating a specific study. See University of Rochester's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Primary Insomnia condition card totals 13 registered trials; most-linked intervention Zolpidem; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.