Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Primary Biliary Cirrhosis: early-phase trial registry
1 of 8 indexed Primary Biliary Cirrhosis trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 1 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Primary Biliary Cirrhosis: 8 US clinical trials tracked, 1 recruiting.
Primary Biliary Cirrhosis is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is NGM Biopharmaceuticals, running 1 of these trials.
Enrollment posture brief
Registry condition primary-biliary-cirrhosis
OPEN 1 | RECR 13% | LATE 2 | EARLY 4 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Infection (13% recruiting · 8 trials)
Primary Biliary Cirrhosis lists 1 open slots (13% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Primary Biliary Cirrhosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Primary Biliary Cirrhosis is recruiting below its size-band peers.
1 of 8 indexed trials (12.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Primary Biliary Cirrhosis trials is spread across many organizations.
NGM Biopharmaceuticals accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Primary Biliary Cirrhosis enrolment sits around 124 participants.
Median target enrolment is 124 among the 8 trials that report a genuine target (sentinel values excluded). 4 of those (50%) plan for fewer than 100 participants.
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Primary Biliary Cirrhosis research is mostly interventional.
6 interventional and 2 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Biobank for Cholestatic Liver Diseases.
Mayo Clinic
NCT03445585
Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)
Gilead Sciences
NCT03301506
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
Ipsen
NCT04526665
Identification of Inflammatory and Fibrotic Biomarkers in PBC and NAFLD Patients
University of California, Davis
NCT02477462
Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis
Mirum Pharmaceuticals
NCT01904058
Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis
Zydus Therapeutics
NCT03112681
Phase 2b Study of NGM282 Extended Treatment in Patients With Primary Biliary Cirrhosis
NGM Biopharmaceuticals
NCT02135536
Use of Fenofibrate for Primary Biliary Cirrhosis
University of Florida
NCT00575042
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 4 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Primary Biliary Cirrhosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Primary Biliary Cirrhosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Primary Biliary Cirrhosis page
8 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 1 Primary Biliary Cirrhosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- NGM Biopharmaceuticals sponsors the most Primary Biliary Cirrhosis trials on record, review their full trial history before evaluating a specific study. See NGM Biopharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Primary Biliary Cirrhosis condition card totals 8 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.