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ClinicalTrials.gov 7 recruiting now early-phase tilt

Prematurity: early-phase trial registry

7 of 22 indexed Prematurity trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 7 currently recruiting · #756 of 28,707 conditions by registered trial count

Prematurity: 22 US clinical trials tracked, 7 recruiting.

Prematurity is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Virginia, running 2 of these trials.

Enrollment posture brief

Registry condition prematurity

OPEN 7 | RECR 32% | LATE 1 | EARLY 2 | RANK #756 | SPON 2

Nearest open-share peer: Childhood Obesity (32% recruiting · 44 trials)

Advanced Melanoma63.6%Prematurity (this)32%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Prematurity

Prematurity lists 7 open slots (32% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prematurity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prematurity is recruiting below its size-band peers.

    7 of 22 indexed trials (31.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prematurity trials is spread across many organizations.

    University of Virginia accounts for 2 of 22 trials (9.1%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prematurity enrolment sits around 118 participants.

    Median target enrolment is 118 among the 22 trials that report a genuine target (sentinel values excluded). 11 of those (50%) plan for fewer than 100 participants.

  4. Prematurity splits between interventional and observational designs.

    12 interventional and 10 observational studies make up this index (54.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22Phase 31

Open and recent trials

22 total, page 1 of 1

RECRUITING 500 participants

Evaluating Wearable Smart Sensors for Continuous Measurement of Vital Signs in ICU Patients

Ann & Robert H Lurie Children's Hospital of Chicago

NCT04723654

RECRUITING NA 486 participants

Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial

University of Alabama at Birmingham

NCT06420531

RECRUITING NA 360 participants

Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy

Case Western Reserve University

NCT06965530

RECRUITING NA 243 participants

The Impact of Music Medicine on Preterm Brain Development and Behavior

Brigham and Women's Hospital

NCT06536296

RECRUITING Phase 2 120 participants

Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants

University of Washington

NCT05340465

RECRUITING 120 participants

Maternal Stress, Milk Composition, and Preterm Neurodevelopment

University of Minnesota

NCT05537454

RECRUITING NA 118 participants

The Effects of Entrainment on Respiratory Stability and Cerebral Oxygenation in Preterm Infants

Icahn School of Medicine at Mount Sinai

NCT05223192

ACTIVE NOT RECRUITING 118 participants

Is There a Microbiome Associated With Poor Growth in Preterm Infants?

University of Texas Southwestern Medical Center

NCT03761498

ACTIVE NOT RECRUITING NA 80 participants

Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants

University of Alabama at Birmingham

NCT05525585

ACTIVE NOT RECRUITING 51 participants

Microbiome, Atopic Disease, Prematurity

Sydney Leibel

NCT04835935

ACTIVE NOT RECRUITING 51 participants

Post-Discharge Growth of Infants Who Received Donor Human Milk Products in the Neonatal Intensive Care Unit (NICU)

Baylor College of Medicine

NCT01483079

COMPLETED 835 participants

Prematurity and Respiratory Outcomes Program (PROP)

University of Pennsylvania

NCT01435187

COMPLETED Phase 3 630 participants

Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial

Yale University

NCT00033917

COMPLETED 277 participants

Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies

University of Rochester

NCT01607216

COMPLETED NA 88 participants

Trial of a Limited Versus Traditional Oxygen Strategy During Resuscitation in Premature Newborns

University of Texas Southwestern Medical Center

NCT01697904

COMPLETED NA 70 participants

NEO Rehab Program for Premature Infants at Risk for Cerebral Palsy

University of Virginia

NCT04330859

COMPLETED Phase 2 66 participants

Initiation of Oral Feeding at 30 Versus 33 Weeks Postmenstrual Age

The University of Texas Health Science Center, Houston

NCT01787019

COMPLETED 63 participants

Study of Generalized Movements for Early Prediction of Cerebral Palsy

Charles R. Neal,

NCT00749008

COMPLETED 60 participants

Neurophysiology and Anatomy of Severe Intraventricular Hemorrhage (IVH)

Vanderbilt University

NCT00817310

COMPLETED 56 participants

Preterm Infants and Nephrocalcinosis

University of Utah

NCT02438267

COMPLETED NA 29 participants

Collaborative Research Group for Necrotizing Enterocolitis

Washington University School of Medicine

NCT00828451

COMPLETED NA 14 participants

NEO Rehab for Infants at Risk of Cerebral Palsy

University of Virginia

NCT03372590

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on Prematurity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Titration of oxygen during newborn resuscitation in delivery room Procedure
1 trials
indomethacin Drug
1 trials
[5,5,5-2H3]leucine (stable isotope labeled leucine) Biological
1 trials
NICU-based rehabilitation bundle Other
1 trials
NeoRehab Bundle Other
1 trials
Oral feeding Other
1 trials
Delayed HMF Dietary supplement
1 trials
Early HMF Dietary supplement
1 trials

US sites by state

Facility locations filed on Prematurity trials. A trial with sites in several states counts in each.

Texas 6 trials
New York 3 trials
Virginia 2 trials
Tennessee 2 trials
Ohio 2 trials
Missouri 2 trials
Connecticut 2 trials
California 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prematurity page

22 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prematurity condition card totals 22 registered trials; most-linked intervention Titration of oxygen during newborn resuscitation in delivery room; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.