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NCT00828451 · ClinicalTrials.gov registry record · NA
Collaborative Research Group for Necrotizing Enterocolitis
A NA study of Prematurity and Necrotizing Enterocolitis, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 29
- Enrollment target
- 1
- Study location
NCT00828451: Completed NA study of Prematurity and Necrotizing Enterocolitis, sponsored by Washington University School of Medicine.
NCT00828451 is a NA study of Prematurity and Necrotizing Enterocolitis that has completed, run by Washington University School of Medicine. The registered enrollment target is 29 participants, below the 210-participant average among 21 other Prematurity trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00828451, a NA study of Prematurity and Necrotizing Enterocolitis, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
This proposal will test the hypothesis that synthesis and catabolism of epidermal growth factor (EGF), the genotype of the EGF gene, and the microbiome interact to influence EGF expression in infants at risk for necrotizing enterocolitis (NEC).
Primary Outcome
Salivary EGF protein levels obtained from oral swabs were analyzed by commercially available EGF ELISA kit (R \&D systems Inc). EGF protein levels were normalized to micrograms of protein in saliva, and expressed as picogram of EGF protein per microgram of total salivary protein.
Conditions Studied
Interventions
- BIOLOGICAL [5,5,5-2H3]leucine (stable isotope labeled leucine)
Study Locations (1)
Missouri
- St. Louis Children's Hospital - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2008-05 |
| Est. Completion | 2010-12 |
| Phase | NA |
What the finished NCT00828451 record still lists
NCT00828451 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 210-participant average among 21 other Prematurity trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Prematurity appearing as the primary indexed condition, and to 1 intervention - of which [5,5,5-2H3]leucine (stable isotope labeled leucine) is the first listed.
NCT00828451 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT00828451 about?
NCT00828451 is a clinical study titled "Collaborative Research Group for Necrotizing Enterocolitis". This proposal will test the hypothesis that synthesis and catabolism of epidermal growth factor (EGF), the genotype of the EGF gene, and the microbiome interact to influence EGF expression in infants at risk for necrotizing enterocolitis (NEC).
What is the current status of trial NCT00828451?
This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2008-05. Estimated completion is 2010-12.
What conditions does trial NCT00828451 study?
This clinical trial studies the following conditions: Prematurity, Necrotizing Enterocolitis.
What interventions are being tested in trial NCT00828451?
The interventions under investigation include: [5,5,5-2H3]leucine (stable isotope labeled leucine) (BIOLOGICAL).
Who is sponsoring clinical trial NCT00828451?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00828451 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00828451's enrollment target sits among peer trials
29 21st of 21 higher than 1 of 21 other Prematurity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prematurity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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