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ClinicalTrials.gov 3 recruiting now later-stage tilt small index

Postoperative Nausea and Vomiting: later-stage trial registry

3 of 11 indexed Postoperative Nausea and Vomiting trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 3 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Postoperative Nausea and Vomiting: 11 US clinical trials tracked, 3 recruiting.

Postoperative Nausea and Vomiting is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Acacia Pharma, running 2 of these trials.

Enrollment posture brief

Registry condition postoperative-nausea-and-vomiting

OPEN 3 | RECR 27% | LATE 4 | EARLY 2 | RANK #1577 | SPON 2

Nearest open-share peer: Atherosclerotic Cardiovascular Disease (27% recruiting · 22 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Postoperative Nausea and (th…27%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting lists 3 open slots (27% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Postoperative Nausea and Vomiting on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Postoperative Nausea and Vomiting is recruiting below its size-band peers.

    3 of 11 indexed trials (27.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Postoperative Nausea and Vomiting research.

    Acacia Pharma accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Postoperative Nausea and Vomiting enrolment sits around 132 participants.

    Median target enrolment is 132 among the 11 trials that report a genuine target (sentinel values excluded). 0 of those (0%) plan for fewer than 100 participants.

  4. Postoperative Nausea and Vomiting research is mostly interventional.

    8 interventional and 3 observational studies make up this index (72.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22Phase 33Phase 41

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 2 132 participants

Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery

United States Naval Medical Center, Portsmouth

NCT06488001

RECRUITING NA 100 participants

Use of Transcutaneous Electrical Nerve Stimulation Device, Reletex Reliefband, With Current ERAS (Enhanced Recovery After Surgery) Protocol to Further Decrease Postoperative Nausea and Vomiting in the Bariatric Surgical Patient Within the First 24 Hours Postoperatively.

University of Pennsylvania

NCT07063979

RECRUITING Phase 3 100 participants

A Pilot Study to Evaluate Barhemsys for the Prevention of Postoperative Nausea and Vomiting in the Bariatric Surgery Population

Benaroya Research Institute

NCT06585540

COMPLETED 2,000 participants

Development of a Predictive Model for Post-Discharge Nausea and Vomiting (PDNV)

University of California, San Francisco

NCT00514878

COMPLETED Phase 3 705 participants

Study of APD421 as PONV Treatment (Prior Prophylaxis)

Acacia Pharma

NCT02646566

COMPLETED Phase 3 515 participants

Casopitant And ZOFRAN To Prevent Post Operative Nausea And Vomiting In Women

GlaxoSmithKline

NCT00334152

COMPLETED Phase 2 257 participants

Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)

Acacia Pharma

NCT00895830

COMPLETED 208 participants

Clinical Use of Baxter Animated Retching Faces (BARF) Scale in Children

Baylor College of Medicine

NCT02421952

COMPLETED NA 122 participants

The Effect of Electroacustimulation on Postoperative Nausea, Vomiting and Pain in Outpatient Plastic Surgery Patients

University of Wisconsin, Madison

NCT00941005

COMPLETED 100 participants

Costs of Postoperative Nausea and Vomiting in Ambulatory Surgery Patients

The Cleveland Clinic

NCT00858949

COMPLETED Phase 4 100 participants

Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients

Scott and White Hospital & Clinic

NCT00738621

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 3
Phase 4 1

Named interventions

Most-linked intervention names on Postoperative Nausea and Vomiting records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
Electroacustimulation Device
1 trials
APD405 Drug
1 trials
Aprepitant, Dexamethasone, Placebo Drug
1 trials
Aprepitant, Dexamethasone, Ondansetron Drug
1 trials
APD421 Drug
1 trials
casopitant Drug
1 trials
pantoprazole Drug
1 trials

US sites by state

Facility locations filed on Postoperative Nausea and Vomiting trials. A trial with sites in several states counts in each.

Texas 3 trials
North Carolina 3 trials
California 3 trials
Ohio 2 trials
Florida 2 trials
Wisconsin 1 trials
Washington 1 trials
Virginia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Postoperative Nausea and Vomiting page

11 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 3 Postoperative Nausea and Vomiting trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Acacia Pharma sponsors the most Postoperative Nausea and Vomiting trials on record, review their full trial history before evaluating a specific study. See Acacia Pharma's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Postoperative Nausea and Vomiting condition card totals 11 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.