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NCT06488001 · ClinicalTrials.gov registry record · Phase 2
Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery
A Phase 2 study of Postoperative Nausea and Vomiting, sponsored by United States Naval Medical Center, Portsmouth.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 132
- Enrollment target
- 1
- Study location
NCT06488001: Recruiting Phase 2 study of Postoperative Nausea and Vomiting, sponsored by United States Naval Medical Center, Portsmouth.
NCT06488001 is a Phase 2 study of Postoperative Nausea and Vomiting that is actively recruiting participants, run by United States Naval Medical Center, Portsmouth. The registered enrollment target is 132 participants, below the 421-participant average among 10 other Postoperative Nausea and Vomiting trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06488001, a Phase 2 study of Postoperative Nausea and Vomiting, is actively recruiting participants, sponsored by United States Naval Medical Center, Portsmouth.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 132 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79. Researchers will compare a placebo to the active medication. Participants will be asked to take three pills around their surgery, two taken before and one taken the night after.
Primary Outcome
Postoperative nausea and vomiting compared between two groups using Visual Analog Scale from 0-10. A score of 0 indicates no nausea and higher scores reflect progressively greater severity.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG pantoprazole
Study Locations (1)
Virginia
- Naval Medical Center Portsmouth - Portsmouth
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2022-08-26 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT06488001 shows while recruiting
NCT06488001 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 421-participant average among 10 other Postoperative Nausea and Vomiting trials with a reported enrollment target (69% lower).
The record links to 1 condition, with Postoperative Nausea and Vomiting appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06488001 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06488001 about?
NCT06488001 is a clinical study titled "Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery". The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79. Researchers will compare a placebo to the active medication. Participants will be ask...
What is the current status of trial NCT06488001?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 132 participants. The study started on 2022-08-26. Estimated completion is 2026-12.
What conditions does trial NCT06488001 study?
This clinical trial studies the following conditions: Postoperative Nausea and Vomiting.
What interventions are being tested in trial NCT06488001?
The interventions under investigation include: Placebo (DRUG), pantoprazole (DRUG).
Who is sponsoring clinical trial NCT06488001?
This trial is sponsored by United States Naval Medical Center, Portsmouth, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06488001 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Nausea and Vomiting
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06488001's enrollment target sits among peer trials
132 6th of 10 higher than 5 of 10 other Postoperative Nausea and Vomiting trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Nausea and Vomiting trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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