Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06585540 · ClinicalTrials.gov registry record · Phase 3
A Pilot Study to Evaluate Barhemsys for the Prevention of Postoperative Nausea and Vomiting in the Bariatric Surgery Population
A Phase 3 study of Postoperative Nausea and Vomiting, sponsored by Benaroya Research Institute.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06585540: Recruiting Phase 3 study of Postoperative Nausea and Vomiting, sponsored by Benaroya Research Institute.
NCT06585540 is a Phase 3 study of Postoperative Nausea and Vomiting that is actively recruiting participants, run by Benaroya Research Institute. The registered enrollment target is 100 participants, below the 424-participant average among 10 other Postoperative Nausea and Vomiting trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06585540, a Phase 3 study of Postoperative Nausea and Vomiting, is actively recruiting participants, sponsored by Benaroya Research Institute.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
To assess the effectiveness of Amisulpride to treat Post Operative Nausea and Vomiting (PONV) and to assess the effectiveness of Amisulpride to prevent PONV following bariatric surgery.
Primary Outcome
Complete response is defined as no occurrence of vomiting or retching, no nausea score ≥ 1 and no use of rescue medication during their Post Anesthesia Care Unit stay.
Conditions Studied
Interventions
- DRUG Amisulpride IV Prevention
- DRUG Amisulpride IV Treatment
- DRUG Placebo Preventative
- DRUG Placebo Treatment
Study Locations (1)
Washington
- Virginia Mason Medical Center - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-09-13 |
| Est. Completion | 2026-01 |
| Phase | Phase 3 |
What NCT06585540 shows while recruiting
NCT06585540 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 424-participant average among 10 other Postoperative Nausea and Vomiting trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Postoperative Nausea and Vomiting appearing as the primary indexed condition, and to 4 interventions - of which Amisulpride IV Prevention is the first listed.
NCT06585540 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT06585540 about?
NCT06585540 is a clinical study titled "A Pilot Study to Evaluate Barhemsys for the Prevention of Postoperative Nausea and Vomiting in the Bariatric Surgery Population". To assess the effectiveness of Amisulpride to treat Post Operative Nausea and Vomiting (PONV) and to assess the effectiveness of Amisulpride to prevent PONV following bariatric surgery.
What is the current status of trial NCT06585540?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2024-09-13. Estimated completion is 2026-01.
What conditions does trial NCT06585540 study?
This clinical trial studies the following conditions: Postoperative Nausea and Vomiting.
What interventions are being tested in trial NCT06585540?
The interventions under investigation include: Amisulpride IV Prevention (DRUG), Amisulpride IV Treatment (DRUG), Placebo Preventative (DRUG), Placebo Treatment (DRUG).
Who is sponsoring clinical trial NCT06585540?
This trial is sponsored by Benaroya Research Institute, which has 28 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06585540 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Nausea and Vomiting
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06585540's enrollment target sits among peer trials
100 8th of 10 the lowest of 10 other Postoperative Nausea and Vomiting trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Nausea and Vomiting trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Casopitant And ZOFRAN To Prevent Post Operative Nausea And Vomiting In Women
COMPLETED · Phase 3
-
Study of APD421 as PONV Treatment (Prior Prophylaxis)
COMPLETED · Phase 3
-
Use of Transcutaneous Electrical Nerve Stimulation Device, Reletex Reliefband, With Current ERAS (Enhanced Recovery After Surgery) Protocol to Further Decrease Postoperative Nausea and Vomiting in the Bariatric Surgical Patient Within the First 24 Hours Postoperatively.
RECRUITING · NA
-
Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery
RECRUITING · Phase 2
-
Costs of Postoperative Nausea and Vomiting in Ambulatory Surgery Patients
COMPLETED
-
Clinical Use of Baxter Animated Retching Faces (BARF) Scale in Children
COMPLETED
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI