Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Pilon Fracture: later-stage trial registry
2 of 3 indexed Pilon Fracture trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #5,209 of 28,707 conditions by registered trial count.
3 US clinical trials · 2 currently recruiting · #5,209 of 28,707 conditions by registered trial count
Pilon Fracture: 3 US clinical trials tracked, 2 recruiting.
Pilon Fracture is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Major Extremity Trauma Research Consortium, running 1 of these trials.
Enrollment posture brief
Registry condition pilon-fracture
OPEN 2 | RECR 67% | LATE 1 | EARLY 0 | RANK #5209 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)
Pilon Fracture lists 2 open slots (67% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pilon Fracture on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pilon Fracture is recruiting above its size-band peers.
2 of 3 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
3 total, page 1 of 1
Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
University of Missouri-Columbia
NCT03652753
Simplified Post Op Rehabilitation for Ankle and Pilon Fractures
University of Virginia
NCT05280639
Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries
Major Extremity Trauma Research Consortium
NCT03562364
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Pilon Fracture records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pilon Fracture trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pilon Fracture page
3 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Pilon Fracture trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Major Extremity Trauma Research Consortium sponsors the most Pilon Fracture trials on record, review their full trial history before evaluating a specific study. See Major Extremity Trauma Research Consortium's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pilon Fracture condition card totals 3 registered trials; most-linked intervention AlterG anti-gravity treadmill; top US site state Virginia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.