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Persistent Atrial Fibrillation: later-stage trial registry
9 of 16 indexed Persistent Atrial Fibrillation trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,060 of 28,707 conditions by registered trial count.
16 US clinical trials · 9 currently recruiting · #1,060 of 28,707 conditions by registered trial count
Persistent Atrial Fibrillation: 16 US clinical trials tracked, 9 recruiting.
Persistent Atrial Fibrillation is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Vivek Reddy, running 3 of these trials.
Enrollment posture brief
Registry condition persistent-atrial-fibrillation
OPEN 9 | RECR 56% | LATE 1 | EARLY 0 | RANK #1060 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Refractory Acute Myeloid Leukemia (56% recruiting · 64 trials)
Persistent Atrial Fibrillation lists 9 open slots (56% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Persistent Atrial Fibrillation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Persistent Atrial Fibrillation is recruiting above its size-band peers.
9 of 16 indexed trials (56.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Persistent Atrial Fibrillation research.
Vivek Reddy accounts for 3 of 16 trials (18.8%). 12 distinct sponsors appear on at least one study for this condition label.
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Typical Persistent Atrial Fibrillation enrolment sits around 250 participants.
Median target enrolment is 250 among the 16 trials that report a genuine target (sentinel values excluded). 2 of those (12.5%) plan for fewer than 100 participants.
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Persistent Atrial Fibrillation research is mostly interventional.
12 interventional and 4 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
16 total, page 1 of 1
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation
Heart Rhythm Clinical and Research Solutions
NCT04088071
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System
Boston Scientific Corporation
NCT06735534
Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Arrhythmias
Vivek Reddy
NCT06765356
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients
Vivek Reddy
NCT05988411
Endocardial Mapping With the CoreMap EP Mapping System
CoreMap
NCT06529978
SPHERE Per-AF Post-Approval Study
Medtronic Cardiac Ablation Solutions
NCT06858306
Observational Study to Examine the Procedural and Outcomes of AF Ablation Assisted by STAR Apollo™ Mapping System
Kansas City Heart Rhythm Research Foundation
NCT05826665
Medtronic Terminate AF Study
Medtronic Cardiac Surgery
NCT03546374
ARIADNE Clinical Trial
Stavros E Mountantonakis
NCT06747091
Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation
Kardium
NCT05462145
Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation
Boston Scientific Corporation
NCT06096337
STOP Persistent AF PAS
Medtronic Cardiac Ablation Solutions
NCT05005949
AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment
AtriCure
NCT03732794
Randomized Evaluation of Atrial Fibrillation Treatment With Focal Impulse and Rotor Modulation Guided Procedures
Abbott Medical Devices
NCT02274857
Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)
Arash Aryana, MD
NCT03057548
RADAR Clinical Trial
Vivek Reddy
NCT03263702
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Persistent Atrial Fibrillation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Persistent Atrial Fibrillation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Persistent Atrial Fibrillation page
16 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 Persistent Atrial Fibrillation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vivek Reddy sponsors the most Persistent Atrial Fibrillation trials on record, review their full trial history before evaluating a specific study. See Vivek Reddy's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Persistent Atrial Fibrillation condition card totals 16 registered trials; most-linked intervention Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.