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NCT05252000 · ClinicalTrials.gov registry record · NA

Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease

A NA study of Periodontal Diseases, sponsored by The University of Texas Health Science Center, Houston.

Completed
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT05252000: Completed NA study of Periodontal Diseases, sponsored by The University of Texas Health Science Center, Houston.

NCT05252000 is a NA study of Periodontal Diseases that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 20 participants, below the 160-participant average among 15 other Periodontal Diseases trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05252000, a NA study of Periodontal Diseases, has completed, sponsored by The University of Texas Health Science Center, Houston.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to compare clinical outcomes after mechanical debridement of at sites exhibiting plaque induced inflammation with or without adjunctive Antimicrobial photodynamic therapy (aPDT) and to assess the the microbiologic profile before and after treatment with or without aPDT

Primary Outcome

Bleeding on probing will be evaluated by gently sweeping the periodontal probe just within the gingival sulcus of the tooth and the presence or absence of bleeding will be recorded .The change is reported as \[(number of bleeding sites (bleeding on probing) at the re-evaluation appointment(4 to 6 weeks after baseline) - (number of bleeding sites (bleeding on probing) at baseline)\] - a negative value indicated less bleeding sites.

Conditions Studied

Interventions

  • DEVICE mechanical debridement
  • DEVICE adjunctive aPDT
  • DEVICE sham aPDT

Study Locations (1)

Texas

  • The University of Texas Health Science Center at Houston - Houston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2022-04-26
Est. Completion 2023-10-10
Phase NA

What the finished NCT05252000 record still lists

NCT05252000 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 160-participant average among 15 other Periodontal Diseases trials with a reported enrollment target (87% lower).

The record links to 1 condition, with Periodontal Diseases appearing as the primary indexed condition, and to 3 interventions - of which mechanical debridement is the first listed.

NCT05252000 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05252000 about?

NCT05252000 is a clinical study titled "Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease". The purpose of this study is to compare clinical outcomes after mechanical debridement of at sites exhibiting plaque induced inflammation with or without adjunctive Antimicrobial photodynamic therapy (aPDT) and to assess the the microbiologic profile before and after treatment with or without aPDT

What is the current status of trial NCT05252000?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2022-04-26. Estimated completion is 2023-10-10.

What conditions does trial NCT05252000 study?

This clinical trial studies the following conditions: Periodontal Diseases.

What interventions are being tested in trial NCT05252000?

The interventions under investigation include: mechanical debridement (DEVICE), adjunctive aPDT (DEVICE), sham aPDT (DEVICE).

Who is sponsoring clinical trial NCT05252000?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05252000 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Periodontal Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05252000's enrollment target sits among peer trials

20 15th of 15 higher than 1 of 15 other Periodontal Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Periodontal Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05252000, the US trial registry maintained by the National Library of Medicine. NCT05252000 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.