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NCT06149585 · ClinicalTrials.gov registry record
Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement
A clinical trial of Microbial Colonization and Periodontal Diseases, sponsored by Case Western Reserve University.
- Recruiting
- Registry status
- 12
- Enrollment target
- 1
- Study location
NCT06149585: Recruiting study of Microbial Colonization and Periodontal Diseases, sponsored by Case Western Reserve University.
NCT06149585 is a study of Microbial Colonization and Periodontal Diseases that is actively recruiting participants, run by Case Western Reserve University. The registered enrollment target is 12 participants, below the 12,654-participant average among 20 other Microbial Colonization trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06149585, a study of Microbial Colonization and Periodontal Diseases, is actively recruiting participants, sponsored by Case Western Reserve University.
- RECRUITING
- Registry status
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in subjects affected by severe periodontitis; to evaluate if microbiome changes in relation to the used of different implant material/surface; and to assess the variance of the changes to determine the sample size for future longitudinal prospective studies.
Primary Outcome
To analyze the oral microbiome modulations through DNA analysis of microbial samples occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in subjects affected by severe periodontitis
Conditions Studied
Interventions
- OTHER Microbial Sampling
Study Locations (1)
Ohio
- Case Western Reserve University Department of Periodontics - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2023-08-16 |
| Est. Completion | 2027-05-01 |
What NCT06149585 shows while recruiting
NCT06149585 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 12,654-participant average among 20 other Microbial Colonization trials with a reported enrollment target (100% lower).
The record links to 4 conditions, with Microbial Colonization appearing as the primary indexed condition, and to 1 intervention - of which Microbial Sampling is the first listed.
NCT06149585 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06149585 about?
NCT06149585 is a clinical study titled "Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement". The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in subjects affected by severe periodontitis; to evaluate if microbiome change...
What is the current status of trial NCT06149585?
This trial is currently recruiting. The enrollment target is 12 participants. The study started on 2023-08-16. Estimated completion is 2027-05-01.
What conditions does trial NCT06149585 study?
This clinical trial studies the following conditions: Microbial Colonization, Periodontal Diseases, Periodontitis, Adult, Edentulous Mouth.
What interventions are being tested in trial NCT06149585?
The interventions under investigation include: Microbial Sampling (OTHER).
Who is sponsoring clinical trial NCT06149585?
This trial is sponsored by Case Western Reserve University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06149585 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Microbial Colonization
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06149585's enrollment target sits among peer trials
12 19th of 20 higher than 2 of 20 other Microbial Colonization trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Microbial Colonization trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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