Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Overdose: later-stage trial registry
4 of 14 indexed Overdose trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,230 of 28,707 conditions by registered trial count.
14 US clinical trials · 4 currently recruiting · #1,230 of 28,707 conditions by registered trial count
Overdose: 14 US clinical trials tracked, 4 recruiting.
Overdose is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Kaiser Permanente, running 2 of these trials.
Enrollment posture brief
Registry condition overdose
OPEN 4 | RECR 29% | LATE 1 | EARLY 0 | RANK #1230 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acne Scars (29% recruiting · 7 trials)
Overdose lists 4 open slots (29% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Overdose on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Overdose is recruiting below its size-band peers.
4 of 14 indexed trials (28.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Overdose trials is spread across many organizations.
Kaiser Permanente accounts for 2 of 14 trials (14.3%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Overdose enrolment sits around 249 participants.
Median target enrolment is 249 among the 14 trials that report a genuine target (sentinel values excluded). 6 of those (42.9%) plan for fewer than 100 participants.
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Overdose research is mostly interventional.
11 interventional and 3 observational studies make up this index (78.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
14 total, page 1 of 1
Emergency Medicine Peer Outreach Worker Engagement for Recovery
University of California, Los Angeles
NCT06320015
Community-based Education, Navigation, and Support Intervention for Military Veterans
New York University
NCT05343169
Shelter HArm Reduction Evaluation
NYU Langone Health
NCT07170072
A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk
Boston Medical Center
NCT07022717
The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy
Kaiser Permanente
NCT03337009
Motivational Interviewing to Increase Uptake of Drug Checking and Safe Drug Use Behaviors to Reduce Overdose
University of California, San Diego
NCT06855836
Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorders (PLI-MOUD)
University of Arkansas
NCT05776823
The Ganchero Intervention for Migrant People Who Inject Drugs From Puerto Rico in New York City
North Jersey AIDS Alliance dba North Jersey Community Research Initiative (NJCRI)
NCT06316739
Improving Access to Naloxone to Prevent Opioid Overdose Deaths (SAIA-Naloxone)
RTI International
NCT05886712
Evaluation of a Medication Health Center to Promote Opioid Safety
Kaiser Permanente
NCT06456294
Monitoring of Overdose Patients With and Without Supplemental Oxygen in the Emergency Department
Hennepin Healthcare Research Institute
NCT02101424
Project POINT: Effectiveness and Scalability of an Overdose Survivor Intervention
Indiana University
NCT03336268
Rapid Initiation of Drug Treatment Engagement
University of Pennsylvania
NCT03908437
AWAITS: A Web-based E-health Application for Active Illicit Opioid Users
University of Cincinnati
NCT03402672
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Overdose records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Overdose trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Overdose page
14 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Overdose trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Kaiser Permanente sponsors the most Overdose trials on record, review their full trial history before evaluating a specific study. See Kaiser Permanente's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Overdose condition card totals 14 registered trials; most-linked intervention POINT; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.