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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Oral Mucositis: early-phase trial registry

4 of 11 indexed Oral Mucositis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 4 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Oral Mucositis: 11 US clinical trials tracked, 4 recruiting.

Oral Mucositis is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is St. Jude Children's Research Hospital, running 2 of these trials.

Enrollment posture brief

Registry condition oral-mucositis

OPEN 4 | RECR 36% | LATE 1 | EARLY 7 | RANK #1577 | SPON 2

Nearest open-share peer: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (36% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Oral Mucositis (this)36%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Oral Mucositis

Oral Mucositis lists 4 open slots (36% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Oral Mucositis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Oral Mucositis is recruiting below its size-band peers.

    4 of 11 indexed trials (36.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Oral Mucositis research.

    St. Jude Children's Research Hospital accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Oral Mucositis enrolment sits around 78 participants.

    Median target enrolment is 78 among the 11 trials that report a genuine target (sentinel values excluded). 6 of those (54.5%) plan for fewer than 100 participants.

  4. Oral Mucositis research is mostly interventional.

    11 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 26Phase 31

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 2 216 participants

RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer

EpicentRx

NCT05966194

RECRUITING NA 100 participants

F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)

Georgetown University

NCT06315855

RECRUITING Phase 2 60 participants

Coconut Oil to Prevent Mouth Sores in Pediatric Patients Receiving High Dose Chemotherapy

Wake Forest University Health Sciences

NCT05441813

RECRUITING NA 20 participants

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

Dana-Farber Cancer Institute

NCT05335434

ACTIVE NOT RECRUITING Phase 2 78 participants

Photobiomodulation for the Prevention of Oral Mucositis

Brigham and Women's Hospital

NCT07290413

ACTIVE NOT RECRUITING Phase 2 60 participants

MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients

MitoImmune Therapeutics

NCT04651634

COMPLETED Phase 3 266 participants

DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer

Soligenix

NCT03237325

COMPLETED Phase 2 110 participants

Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer

Izun Pharma

NCT01400620

COMPLETED Phase 2 104 participants

Miracle Mouthwash Plus Hydrocortisone vs Prednisolone Mouth Rinse for Mouth Sores Caused by Everolimus

US Oncology Research

NCT02229136

COMPLETED NA 43 participants

Prevention of Oral Mucositis Using Photobiomodulation Therapy

St. Jude Children's Research Hospital

NCT04227340

COMPLETED Phase 1 19 participants

Dose Escalation Study Of Palifermin in Pediatric Research Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

St. Jude Children's Research Hospital

NCT00701688

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 6
Phase 3 1

Named interventions

Most-linked intervention names on Oral Mucositis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

SGX942 Drug
1 trials
IZN-6N4 Drug
1 trials
Miracle Mouthwash Plus Hydrocortisone Drug
1 trials
Parent-Reported Satisfaction Survey Other
1 trials
Pain and Oral Function Assessment Other
1 trials
Photobiomodulation Therapy (PBM) Device
1 trials
MIT-001 plus CCRT Drug
1 trials
Photobiomodulation - INTRAORAL and EXTRAORAL Device
1 trials

US sites by state

Facility locations filed on Oral Mucositis trials. A trial with sites in several states counts in each.

Tennessee 3 trials
North Carolina 3 trials
Florida 3 trials
Arizona 3 trials
Texas 2 trials
Ohio 2 trials
New York 2 trials
Nevada 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Oral Mucositis page

11 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Oral Mucositis condition card totals 11 registered trials; most-linked intervention SGX942; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.