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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Opioid Use, Unspecified: early-phase trial registry

2 of 10 indexed Opioid Use, Unspecified trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 2 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Opioid Use, Unspecified: 10 US clinical trials tracked, 2 recruiting.

Opioid Use, Unspecified is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.

Enrollment posture brief

Registry condition opioid-use-unspecified

OPEN 2 | RECR 20% | LATE 1 | EARLY 2 | RANK #1724 | SPON 2

Nearest open-share peer: Acral Lentiginous Melanoma (20% recruiting · 5 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%Opioid Use, Unspecified (thi…20%
Open-enrollment share among volume-matched conditions near Opioid Use, Unspecified

Opioid Use, Unspecified lists 2 open slots (20% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Opioid Use, Unspecified on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Opioid Use, Unspecified is recruiting below its size-band peers.

    2 of 10 indexed trials (20%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Opioid Use, Unspecified research.

    Northwestern University accounts for 2 of 10 trials (20%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical Opioid Use, Unspecified enrolment sits around 105 participants.

    Median target enrolment is 105 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.

  4. Opioid Use, Unspecified research is mostly interventional.

    8 interventional and 2 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 41

Open and recent trials

10 total, page 1 of 1

RECRUITING 600 participants

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Senthil Sadhasivam

NCT03923374

RECRUITING 40 participants

Sensory Outcomes in Active Substance Users

Boston Medical Center

NCT06639438

ACTIVE NOT RECRUITING NA 163 participants

Patient Utilization of Opioid Destruction Bags in the Post-op Period

University of Nebraska

NCT05875857

ACTIVE NOT RECRUITING Phase 2 62 participants

Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement

Beth Israel Deaconess Medical Center

NCT05283980

COMPLETED NA 652 participants

EHR-Based Medication Complete Communication Strategy to Promote Safe Opioid Use

Northwestern University

NCT02431793

COMPLETED NA 278 participants

Prescribing Opioid Pain Relievers in the Emergency Department: Understanding and Optimizing the Encounter

Northwestern University

NCT02299024

COMPLETED Phase 4 105 participants

the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block

Montefiore Medical Center

NCT02653144

COMPLETED NA 96 participants

Controlled Substance Treatment Agreements in an Internal Medicine Residents' Clinic

Ohio State University

NCT02244099

COMPLETED NA 41 participants

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety (AESOPS): R21 Pilot Phase

University of Southern California

NCT03773484

COMPLETED Phase 1 13 participants

Opioid Modulation and Neural Reward Activation in Healthy Adults

University of Colorado, Denver

NCT04854551

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Opioid Use, Unspecified records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Additional Opioid Information Behavioral
1 trials
SMS Text Reminders Behavioral
1 trials
EMC2 Strategy Behavioral
1 trials
At-risk for long term use Behavioral
1 trials
Opioid naive Behavioral
1 trials
Controlled Substance Other
1 trials
Long-term opioid recipient Behavioral
1 trials
0.25% Bupivacaine Drug
1 trials

US sites by state

Facility locations filed on Opioid Use, Unspecified trials. A trial with sites in several states counts in each.

Illinois 3 trials
Massachusetts 2 trials
Pennsylvania 1 trials
Ohio 1 trials
New York 1 trials
Nebraska 1 trials
Colorado 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Opioid Use, Unspecified page

10 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opioid Use, Unspecified condition card totals 10 registered trials; most-linked intervention Additional Opioid Information; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.