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NCT03923374 · ClinicalTrials.gov registry record
Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
A clinical trial of Opioid Use Disorder and Opioid Use, Unspecified, sponsored by Senthil Sadhasivam.
- Recruiting
- Registry status
- 600
- Enrollment target
- 1
- Study location
NCT03923374: Recruiting study of Opioid Use Disorder and Opioid Use, Unspecified, sponsored by Senthil Sadhasivam.
NCT03923374 is a study of Opioid Use Disorder and Opioid Use, Unspecified that is actively recruiting participants, run by Senthil Sadhasivam. The registered enrollment target is 600 participants, below the 4,654-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03923374, a study of Opioid Use Disorder and Opioid Use, Unspecified, is actively recruiting participants, sponsored by Senthil Sadhasivam.
- RECRUITING
- Registry status
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).
Primary Outcome
Incidence of opioid misuse severity and buprenorphine treatment response will be assessed by the treating physician using assessments such as Who Assist, TCU Motform, Adverse Childhood Experience Assessment, Ham-A and Ham-D.
Conditions Studied
Interventions
- DRUG Subutex / Buprenorphine
- DIAGNOSTIC_TEST Fetal & Neonatal MRI
- DIAGNOSTIC_TEST DNA/Genetic/Pharmacokenetic Blood Draws
Study Locations (1)
Pennsylvania
- UPMC Children's Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2018-09-15 |
| Est. Completion | 2026-12-30 |
What NCT03923374 shows while recruiting
NCT03923374 is an observational study that tracks outcomes without assigning an intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 4,654-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (87% lower).
The record links to 3 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 3 interventions - of which Subutex / Buprenorphine is the first listed.
NCT03923374 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03923374 about?
NCT03923374 is a clinical study titled "Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes". The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).
What is the current status of trial NCT03923374?
This trial is currently recruiting. The enrollment target is 600 participants. The study started on 2018-09-15. Estimated completion is 2026-12-30.
What conditions does trial NCT03923374 study?
This clinical trial studies the following conditions: Opioid Use Disorder, Opioid Use, Unspecified, Buprenorphine Dependence.
What interventions are being tested in trial NCT03923374?
The interventions under investigation include: Subutex / Buprenorphine (DRUG), Fetal & Neonatal MRI (DIAGNOSTIC_TEST), DNA/Genetic/Pharmacokenetic Blood Draws (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03923374?
This trial is sponsored by Senthil Sadhasivam, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03923374 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Opioid Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03923374's enrollment target sits among peer trials
600 27th of 257 higher than 228 of 257 other Opioid Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Opioid Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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