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Opioid Misuse
Open-data reference.
14 US clinical trials · 4 currently recruiting
Active & Recent Trials
M2VA Pain Care Pathway
Yale University
NCT06526143
CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial
Stanford University
NCT06027099
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
University of New Mexi
NCT06565416
Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention
University of Wisconsin, Madison
NCT06527599
Healthy Opioid Prescription Engagement
Jerry Cochran
NCT05141266
Pain Care at Home to Amplify Function (Pain CHAMP)
Yale University
NCT05333341
Reduced Opioid Prescription After Laparoscopic Hysterectomy
Johns Hopkins University
NCT05548582
Natural Language Processing for Screening Opioid Misuse
University of Wisconsin, Madison
NCT05745480
Increasing Implementation of Post-Operative Opioid Prescribing Guidelines
University of Pennsylvania
NCT05358522
Parenting Young Children Study
University of Oregon
NCT05180487
Decreasing Opioid Misuse and Habit-forming Behaviors Following Prescription in Patients Undergoing Cesarean Section
Jessica Morgan
NCT05461196
Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed Long-term Opioid Therapy
University of Pittsburgh
NCT05182606
Opioid Education in Total Knee Arthroplasty
Hospital for Special Surgery, New York
NCT05593341
A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers
Yale University
NCT04109599
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Opioid Misuse Trial Landscape
ClinicalTrials.gov lists 14 US studies indexed under Opioid Misuse, and 4 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Opioid Misuse shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Opioid Misuse is led by Yale University with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Opioid Misuse?
PlainTrial tracks 14 US clinical trials for Opioid Misuse, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Opioid Misuse?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.