Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Opioid Misuse: later-stage trial registry
4 of 14 indexed Opioid Misuse trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,230 of 28,707 conditions by registered trial count.
14 US clinical trials · 4 currently recruiting · #1,230 of 28,707 conditions by registered trial count
Opioid Misuse: 14 US clinical trials tracked, 4 recruiting.
Opioid Misuse is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 3 of these trials.
Enrollment posture brief
Registry condition opioid-misuse
OPEN 4 | RECR 29% | LATE 1 | EARLY 0 | RANK #1230 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acne Scars (29% recruiting · 7 trials)
Opioid Misuse lists 4 open slots (29% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Opioid Misuse on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Opioid Misuse is recruiting below its size-band peers.
4 of 14 indexed trials (28.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Opioid Misuse research.
Yale University accounts for 3 of 14 trials (21.4%). 11 distinct sponsors appear on at least one study for this condition label.
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Typical Opioid Misuse enrolment sits around 259 participants.
Median target enrolment is 259 among the 14 trials that report a genuine target (sentinel values excluded). 3 of those (21.4%) plan for fewer than 100 participants.
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Opioid Misuse research is mostly interventional.
13 interventional and 1 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
14 total, page 1 of 1
M2VA Pain Care Pathway
Yale University
NCT06526143
CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial
Stanford University
NCT06027099
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
University of New Mexi
NCT06565416
Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention
University of Wisconsin, Madison
NCT06527599
Healthy Opioid Prescription Engagement
Jerry Cochran
NCT05141266
Pain Care at Home to Amplify Function (Pain CHAMP)
Yale University
NCT05333341
Reduced Opioid Prescription After Laparoscopic Hysterectomy
Johns Hopkins University
NCT05548582
Natural Language Processing for Screening Opioid Misuse
University of Wisconsin, Madison
NCT05745480
Increasing Implementation of Post-Operative Opioid Prescribing Guidelines
University of Pennsylvania
NCT05358522
Parenting Young Children Study
University of Oregon
NCT05180487
Decreasing Opioid Misuse and Habit-forming Behaviors Following Prescription in Patients Undergoing Cesarean Section
Jessica Morgan
NCT05461196
Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed Long-term Opioid Therapy
University of Pittsburgh
NCT05182606
Opioid Education in Total Knee Arthroplasty
Hospital for Special Surgery, New York
NCT05593341
A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers
Yale University
NCT04109599
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Opioid Misuse records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Opioid Misuse trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Opioid Misuse page
14 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Opioid Misuse trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Opioid Misuse trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opioid Misuse condition card totals 14 registered trials; most-linked intervention Opioid Prescribing Report Cards; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.