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Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention
NCT06527599 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of the present pilot, sequential, multiple-assignment randomized trial (Pilot SMART) is to determine feasibility and acceptability of delivering (from the perspective of the treatment/intervention staff) and receiving (from the perspective of the patient) an adaptive intervention for reducing rates of opioid misuse and preventing development of opioid use disorder in individuals hospitalized for traumatic injury. A complimentary secondary objective is to ensure the feasibility of conducting a future, multi-site, full-scale SMART. Approximately 107 participants will be enrolled and can expect to be on study for up to 6 months.
Conditions Studied
Interventions
- OTHER Opioid Risk Monitoring (ORM)
- BEHAVIORAL enhanced Trauma Care Coordination (eTCC)
- BEHAVIORAL Pain Coping Skills Training - Brief (PCST-LITE)
- BEHAVIORAL Standard Trauma Care Coordination (sTCC)
- BEHAVIORAL Pain Coping Skills Training - Plus (PCST+)
Study Locations (2)
Wisconsin
- UW Health — Madison
- Medical College of Wisconsin — Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 107 participants |
| Start Date | 2024-08-13 |
| Est. Completion | 2026-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06527599
The ClinicalTrials.gov registry entry for NCT06527599 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 107 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Wisconsin, Madison, which has 943 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Trauma Injury appearing as the primary indexed condition, and to 5 interventions — of which Opioid Risk Monitoring (ORM) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06527599 reports 2 study locations spanning 1 distinct geographic area — top geographies include Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06527599 about?
NCT06527599 is a clinical study titled "Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention". The primary objective of the present pilot, sequential, multiple-assignment randomized trial (Pilot SMART) is to determine feasibility and acceptability of delivering (from the perspective of the treatment/intervention staff) and receiving (from the perspective of the patient) an adaptive interventi...
What is the current status of trial NCT06527599?
This trial is currently recruiting. It is a NA study. The enrollment target is 107 participants. The study started on 2024-08-13. Estimated completion is 2026-06.
What conditions does trial NCT06527599 study?
This clinical trial studies the following conditions: Trauma Injury, Opioid Misuse. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06527599?
The interventions under investigation include: Opioid Risk Monitoring (ORM) (OTHER), enhanced Trauma Care Coordination (eTCC) (BEHAVIORAL), Pain Coping Skills Training - Brief (PCST-LITE) (BEHAVIORAL), Standard Trauma Care Coordination (sTCC) (BEHAVIORAL), Pain Coping Skills Training - Plus (PCST+) (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06527599?
This trial is sponsored by University of Wisconsin, Madison, which has 943 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06527599 being conducted?
This trial has 2 study locations across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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