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NCT05006079 · ClinicalTrials.gov registry record · Phase 2
Opioid/Benzodiazepine Polydrug Abuse: Aim 3
A Phase 2 study of Opioid Abuse and Polysubstance Abuse, sponsored by Wayne State University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05006079: Recruiting Phase 2 study of Opioid Abuse and Polysubstance Abuse, sponsored by Wayne State University.
NCT05006079 is a Phase 2 study of Opioid Abuse and Polysubstance Abuse that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 24 participants, below the 1,544,083-participant average among 10 other Opioid Abuse trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05006079, a Phase 2 study of Opioid Abuse and Polysubstance Abuse, is actively recruiting participants, sponsored by Wayne State University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
In this study, the investigators will measure affective, neurocognitive and behavioral outcomes related to chronic use of opioids and benzodiazepines (screening phase), and in response to the administration of the opioid morphine, the benzodiazepine alprazolam, morphine then alprazolam, alprazolam then morphine, morphine+alprazolam simultaneously, and placebo (laboratory pharmacology experiment). The latter will enable the investigators to assess the effects of an opioid alone, benzodiazepine alone, concurrent and simultaneous administration of opioid+benzodiazepine, relative to a placebo control.
Primary Outcome
State Trait Anxiety Inventory - state anxiety scale total score
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Alprazolam
- DRUG Morphine
Study Locations (1)
Michigan
- Tolan Park Medical Building - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2024-03-13 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT05006079 shows while recruiting
NCT05006079 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,544,083-participant average among 10 other Opioid Abuse trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Opioid Abuse appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05006079 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT05006079 about?
NCT05006079 is a clinical study titled "Opioid/Benzodiazepine Polydrug Abuse: Aim 3". In this study, the investigators will measure affective, neurocognitive and behavioral outcomes related to chronic use of opioids and benzodiazepines (screening phase), and in response to the administration of the opioid morphine, the benzodiazepine alprazolam, morphine then alprazolam, alprazolam t...
What is the current status of trial NCT05006079?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2024-03-13. Estimated completion is 2026-12.
What conditions does trial NCT05006079 study?
This clinical trial studies the following conditions: Opioid Abuse, Polysubstance Abuse, Benzodiazepine Abuse.
What interventions are being tested in trial NCT05006079?
The interventions under investigation include: Placebo (DRUG), Alprazolam (DRUG), Morphine (DRUG).
Who is sponsoring clinical trial NCT05006079?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05006079 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05006079's enrollment target sits among peer trials
24 11th of 10 the lowest of 10 other Opioid Abuse trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Opioid Abuse trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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