Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05006079 · ClinicalTrials.gov registry record · Phase 2
Opioid/Benzodiazepine Polydrug Abuse: Aim 3
A Phase 2 study of Opioid Abuse and Polysubstance Abuse, sponsored by Wayne State University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05006079 is a Phase 2 study of Opioid Abuse and Polysubstance Abuse that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 24 participants, below the 1,544,083-participant average among 10 other Opioid Abuse trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05006079, a Phase 2 study of Opioid Abuse and Polysubstance Abuse, is actively recruiting participants, sponsored by Wayne State University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
In this study, the investigators will measure affective, neurocognitive and behavioral outcomes related to chronic use of opioids and benzodiazepines (screening phase), and in response to the administration of the opioid morphine, the benzodiazepine alprazolam, morphine then alprazolam, alprazolam then morphine, morphine+alprazolam simultaneously, and placebo (laboratory pharmacology experiment). The latter will enable the investigators to assess the effects of an opioid alone, benzodiazepine alone, concurrent and simultaneous administration of opioid+benzodiazepine, relative to a placebo control.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Alprazolam
- DRUG Morphine
Study Locations (1)
Michigan
- Tolan Park Medical Building - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2024-03-13 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05006079
The ClinicalTrials.gov registry entry for NCT05006079 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,544,083-participant average among 10 other Opioid Abuse trials with a reported enrollment target (100% lower). The listed sponsor is Wayne State University, which has 163 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Opioid Abuse appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05006079 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.
Frequently Asked Questions
What is clinical trial NCT05006079 about?
NCT05006079 is a clinical study titled "Opioid/Benzodiazepine Polydrug Abuse: Aim 3". In this study, the investigators will measure affective, neurocognitive and behavioral outcomes related to chronic use of opioids and benzodiazepines (screening phase), and in response to the administration of the opioid morphine, the benzodiazepine alprazolam, morphine then alprazolam, alprazolam t...
What is the current status of trial NCT05006079?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2024-03-13. Estimated completion is 2026-12.
What conditions does trial NCT05006079 study?
This clinical trial studies the following conditions: Opioid Abuse, Polysubstance Abuse, Benzodiazepine Abuse.
What interventions are being tested in trial NCT05006079?
The interventions under investigation include: Placebo (DRUG), Alprazolam (DRUG), Morphine (DRUG).
Who is sponsoring clinical trial NCT05006079?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05006079 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Opioid Abuse
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers
COMPLETED · Phase 2
-
Neuromodulation and Cognitive Training in Opioid Use Disorder
RECRUITING · NA
-
Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment
RECRUITING · NA
-
fMRI and Opioid Abstinence
RECRUITING
-
Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool
ACTIVE NOT RECRUITING · NA
-
Opioid Education in Total Knee Arthroplasty
COMPLETED · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.