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ClinicalTrials.gov 21 recruiting now early-phase tilt

Obesity & Overweight: early-phase trial registry

21 of 29 indexed Obesity & Overweight trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #552 of 28,707 conditions by registered trial count.

29 US clinical trials · 21 currently recruiting · #552 of 28,707 conditions by registered trial count

Obesity & Overweight: 29 US clinical trials tracked, 21 recruiting.

Obesity & Overweight is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 21 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 4 of these trials.

Enrollment posture brief

Registry condition obesity-overweight

OPEN 21 | RECR 72% | LATE 0 | EARLY 4 | RANK #552 | SPON 4

Nearest open-share peer: Cardiomyopathies (72% recruiting · 18 trials)

Obesity & Overweight (this)72%Advanced Breast Cancer62.1%Amyloidosis51.7%Arthritis, Rheumatoid17.2%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Obesity & Overweight

Obesity & Overweight lists 21 open slots (72% of 29 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Obesity & Overweight on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Obesity & Overweight is recruiting above its size-band peers.

    21 of 29 indexed trials (72.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Obesity & Overweight trials is spread across many organizations.

    Yale University accounts for 4 of 29 trials (13.8%). 25 distinct sponsors appear on at least one study for this condition label.

  3. Most Obesity & Overweight trials plan to enrol fewer than 100 people.

    Median target enrolment is 80 among the 29 trials that report a genuine target (sentinel values excluded). 18 of those (62.1%) plan for fewer than 100 participants.

  4. Obesity & Overweight research is mostly interventional.

    26 interventional and 3 observational studies make up this index (89.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 24

Open and recent trials

29 total, page 1 of 1

RECRUITING NA 300 participants

Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity

Wake Forest University Health Sciences

NCT07227051

RECRUITING NA 300 participants

Trial of Food Is Medicine Approaches for Obesity Treatment in Adults With Food Insecurity

Johns Hopkins University

NCT07396805

RECRUITING NA 275 participants

Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment

The Miriam Hospital

NCT07228130

RECRUITING NA 200 participants

Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults

Kennesaw State University

NCT07221279

RECRUITING Phase 2 160 participants

Pharmacological and Behavioral Treatment After Bariatric Surgery: Acute (Stage 1)

Yale University

NCT04599478

RECRUITING NA 120 participants

Stanford Pediatric Healthy Weight Index

Stanford University

NCT07316816

RECRUITING NA 110 participants

Effects of Exercise on Lipids and Endothelial Function in Youth

Children's Hospital Medical Center, Cincinnati

NCT07409064

RECRUITING NA 108 participants

Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy

Ian J. Neeland, MD

NCT07244445

RECRUITING NA 92 participants

Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Participate in a Weight Loss Program, Half Will Receive Bed Scales, and Participants Who Receive the Bed Scales Are Expected to Have Increased Weight Loss.

Jonathan Pearlman

NCT07141342

RECRUITING NA 90 participants

FELLAShip to Better Health

University of Alabama at Birmingham

NCT07220213

RECRUITING NA 80 participants

Feasibility and Acceptability of a Pediatric Referral to Summer Day Camps to Treat Obesity in Children From Low-Income Households

University of Central Florida

NCT07464015

RECRUITING NA 80 participants

Personalizing Financial Incentives

University of Utah

NCT07225426

RECRUITING NA 80 participants

HealthyWE: Achieving a Healthy Weight and Reducing Pain

Rutgers, The State University of New Jersey

NCT07095673

RECRUITING 52 participants

Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study

University of Rochester

NCT07217756

RECRUITING NA 50 participants

Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight

The Miriam Hospital

NCT07363616

RECRUITING NA 50 participants

Fueling Strong Hearts for a Strong South Carolina

Clemson University

NCT07140952

RECRUITING NA 50 participants

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

University of Missouri-Columbia

NCT07231484

RECRUITING NA 50 participants

Sanctuary Farm Prescription in Adolescents

Nemours Children's Clinic

NCT07218588

RECRUITING NA 24 participants

Soup and Bread Recipe Impacts on Ingestive Behavior

USDA Beltsville Human Nutrition Research Center

NCT07146958

RECRUITING NA 20 participants

Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

Cambridge Health Alliance

NCT06988462

RECRUITING NA 20 participants

Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial

Indiana University

NCT07119658

ACTIVE NOT RECRUITING 500 participants

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

Marymount University

NCT07180147

ACTIVE NOT RECRUITING 125 participants

A Consumer Health Study Evaluating the Impact of Pivit on Weight Loss and Appetite in Overweight Individuals

Olfactive Biosolutions

NCT07245914

ACTIVE NOT RECRUITING Phase 2 100 participants

Pharmacological and Behavioral Treatments After Bariatric Surgery: Maintenance Treatment (Stage 2a)

Yale University

NCT04605081

ACTIVE NOT RECRUITING NA 60 participants

E-Bike Commuting and Health in Overweight College Students

University of Wisconsin, River Falls

NCT07114991

ACTIVE NOT RECRUITING Phase 2 60 participants

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

Yale University

NCT04599504

ACTIVE NOT RECRUITING NA 30 participants

Dietary Reversal of the Reprometabolic Syndrome

University of Colorado, Denver

NCT07227766

ACTIVE NOT RECRUITING NA 10 participants

Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension

Texas Woman's University

NCT07130539

COMPLETED Phase 2 26 participants

Weight Regain Treatment Post-Bariatric Surgery

Yale University

NCT04662801

Phase Distribution

PhaseTrial count
Phase 2 4

Named interventions

Most-linked intervention names on Obesity & Overweight records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Other
4 trials
Early Non-responder: BWL continued with medication added Combination
1 trials
Early Responder: BWL continued Behavioral
1 trials
Behavioral Weight Loss (BWL) Behavioral
1 trials
The Study Product (Pivit) Dietary supplement
1 trials
Mind Hiit Other
1 trials
Lisdexamfetamine Dimesylate (Medication) Drug
1 trials
Naltrexone and Bupropion (NB) medication Drug
1 trials

US sites by state

Facility locations filed on Obesity & Overweight trials. A trial with sites in several states counts in each.

Connecticut 4 trials
Wisconsin 2 trials
Rhode Island 2 trials
Pennsylvania 2 trials
Ohio 2 trials
Maryland 2 trials
California 2 trials
Virginia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Obesity & Overweight page

29 registered trials, 21 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 21 Obesity & Overweight trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Yale University sponsors the most Obesity & Overweight trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity & Overweight condition card totals 29 registered trials; most-linked intervention Placebo; top US site state Connecticut. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.