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ClinicalTrials.gov 8 recruiting now official registry

Neuromuscular Diseases clinical trials

Every US clinical trial registered for Neuromuscular Diseases — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

16 US clinical trials · 8 currently recruiting

The research picture

Neuromuscular Diseases has 16 registered US clinical trials, 8 of them open to new participants right now — about 50% of the total.

8
recruiting participants now
50%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
3
top sponsor: Scholar Rock

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 500 participants

CIMR Neuromuscular Research Biobank

Virginia Commonwealth University

NCT05434572

RECRUITING 100 participants

Spastic Paraplegia - Centers of Excellence Research Network

Boston Children's Hospital

NCT06553976

RECRUITING 90 participants

Genesis Electrical Impedance Tomography (EIT): A Preliminary Study

University of Colorado, Denver

NCT03797183

RECRUITING Phase 2 51 participants

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Satellos Bioscience

NCT07287189

RECRUITING 40 participants

Measuring Physical Activity With ActivPal

Columbia University

NCT06084026

RECRUITING 20 participants

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

Elpida Therapeutics SPC

NCT06151600

RECRUITING NA 20 participants

Non-Invasive Respiratory Monitor

Nemours Children's Clinic

NCT02851043

RECRUITING NA 20 participants

Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study

University of Pennsylvania

NCT06119087

ACTIVE NOT RECRUITING Phase 3 269 participants

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy

Biohaven Pharmaceuticals

NCT05337553

ACTIVE NOT RECRUITING Phase 3 238 participants

Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab

Scholar Rock

NCT05626855

ACTIVE NOT RECRUITING Phase 3 106 participants

A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Capricor

NCT05126758

COMPLETED 215 participants

Expediting Myasthenia Gravis (MG) Diagnostic Evaluation: A Novel, Proof-of-Concept for Undiagnosed, Symptomatic Patients That Uses Social Media Targeting and Self-Assessment

ZS Associates

NCT06381284

COMPLETED Phase 3 188 participants

Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam

Scholar Rock

NCT05156320

COMPLETED Phase 2 58 participants

An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy

Scholar Rock

NCT03921528

COMPLETED Phase 2 37 participants

Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients

Avidity Biosciences

NCT05479981

COMPLETED Phase 1 19 participants

Study of Pioglitazone in Sporadic Inclusion Body Myositis

Johns Hopkins University

NCT03440034

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neuromuscular Diseases Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Neuromuscular Diseases, and 8 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Neuromuscular Diseases shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Neuromuscular Diseases is led by Scholar Rock with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neuromuscular Diseases?

PlainTrial tracks 16 US clinical trials for Neuromuscular Diseases, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neuromuscular Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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