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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Neuroendocrine Carcinoma: early-phase trial registry

3 of 14 indexed Neuroendocrine Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 3 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Neuroendocrine Carcinoma: 14 US clinical trials tracked, 3 recruiting.

Neuroendocrine Carcinoma is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition neuroendocrine-carcinoma

OPEN 3 | RECR 21% | LATE 0 | EARLY 12 | RANK #1230 | SPON 4

Nearest open-share peer: Cervical Adenocarcinoma (21% recruiting · 14 trials)

Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Neuroendocrine Carcinoma (th…21%Abscess7.1%
Open-enrollment share among volume-matched conditions near Neuroendocrine Carcinoma

Neuroendocrine Carcinoma lists 3 open slots (21% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Neuroendocrine Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Neuroendocrine Carcinoma is recruiting below its size-band peers.

    3 of 14 indexed trials (21.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Neuroendocrine Carcinoma research.

    M.D. Anderson Cancer Center accounts for 4 of 14 trials (28.6%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Most Neuroendocrine Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 14 trials that report a genuine target (sentinel values excluded). 9 of those (64.3%) plan for fewer than 100 participants.

  4. Neuroendocrine Carcinoma research is mostly interventional.

    12 interventional and 2 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 27

Open and recent trials

14 total, page 1 of 1

RECRUITING Phase 1 220 participants

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Circle Pharma

NCT06577987

RECRUITING Phase 2 60 participants

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

National Cancer Institute (NCI)

NCT06406465

RECRUITING Phase 1 36 participants

SVV-001 With Nivolumab and Ipilimumab in Patients With Poorly Differentiated Neuroendocrine Carcinomas (NEC) or Well-Differentiated High-Grade Neuroendocrine Tumors (NET)

Peter Hosein, MD

NCT06889493

ACTIVE NOT RECRUITING 2,539 participants

Neuroendocrine Tumors - Patient Reported Outcomes

University of Iowa

NCT05064150

ACTIVE NOT RECRUITING Phase 1 232 participants

A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)

Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT04471727

ACTIVE NOT RECRUITING Phase 2 140 participants

Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung Cancer

M.D. Anderson Cancer Center

NCT03110978

ACTIVE NOT RECRUITING Phase 2 133 participants

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

M.D. Anderson Cancer Center

NCT03074513

ACTIVE NOT RECRUITING Phase 2 55 participants

Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

Dwight Owen

NCT03728361

ACTIVE NOT RECRUITING Phase 2 48 participants

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

M.D. Anderson Cancer Center

NCT04701307

ACTIVE NOT RECRUITING Phase 1 33 participants

Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors

Vyriad

NCT03647163

ACTIVE NOT RECRUITING 30 participants

Use of 68Ga-dotatate PET Scan in Neuroendocrine Carcinoma of the GI Tract

H. Lee Moffitt Cancer Center and Research Institute

NCT04069299

ACTIVE NOT RECRUITING Phase 1 15 participants

NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomas

Amr Mohamed MD

NCT05262556

COMPLETED Phase 2 67 participants

RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma

M.D. Anderson Cancer Center

NCT00113360

COMPLETED Phase 2 43 participants

Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers

SCRI Development Innovations

NCT01121939

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 7

Named interventions

Most-linked intervention names on Neuroendocrine Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Nivolumab Biological
2 trials
Sandostatin LAR® Depot Drug
1 trials
Octreotide Depot Drug
1 trials
ipilimumab + nivolumab Biological
1 trials
VSV-IFNβ-NIS Biological
1 trials
RAD001 Drug
1 trials
Positron Emission Tomography (PET) Scan Diagnostic test
1 trials
Ipilimumab (1mg/kg) Drug
1 trials

US sites by state

Facility locations filed on Neuroendocrine Carcinoma trials. A trial with sites in several states counts in each.

Ohio 7 trials
Texas 6 trials
Florida 5 trials
Tennessee 4 trials
Michigan 4 trials
Wisconsin 2 trials
Utah 2 trials
Oregon 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Neuroendocrine Carcinoma page

14 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neuroendocrine Carcinoma condition card totals 14 registered trials; most-linked intervention Nivolumab; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.