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NCT01121939 · ClinicalTrials.gov registry record · Phase 2

Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers

A Phase 2 study of Neuroendocrine Carcinoma, sponsored by SCRI Development Innovations.

Completed
Registry status
Phase 2
Development phase
43
Enrollment target
9
Study locations

NCT01121939 is a Phase 2 study of Neuroendocrine Carcinoma that has completed, run by SCRI Development Innovations. The registered enrollment target is 43 participants, below the 278-participant average among 13 other Neuroendocrine Carcinoma trials with a reported enrollment target (85% lower). The trial reports 9 study locations across 8 states.

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The verdict

NCT01121939, a Phase 2 study of Neuroendocrine Carcinoma, has completed, sponsored by SCRI Development Innovations.

COMPLETED
Registry status
Phase 2
Development phase
43 participants
Enrollment target
9
Study locations

Study Summary

The purpose of this Phase II trial will be to define the activity of a VEGF inhibitor bevacizumab, HER1/HER2 inhibitor pertuzumab, and sandostatin for patients with advanced neuroendocrine cancers. In particular, the efficacy of bevacizumab and pertuzumab treatment is of great interest. The primary endpoint of this trial will be response rate. Toxicity and progression-free survival will be obtained and evaluated.

Conditions Studied

Interventions

  • DRUG Bevacizumab
  • DRUG Pertuzumab
  • DRUG Sandostatin LAR® Depot

Study Locations (9)

Florida

  • Florida Cancer Specialists - Fort Myers
  • Florida Hospital Cancer Institute - Orlando

Georgia

  • Medical Oncology Associates of Augusta - Augusta

Kentucky

  • Baptist Medical Center East - Louisville

Michigan

  • Grand Rapids Oncology Program - Grand Rapids

Missouri

  • Research Medical Center - Kansas City

New Jersey

  • Hematology-Oncology Associates of Northern NJ - Morristown

Ohio

  • Oncology Hematology Care, Inc - Cincinnati

Tennessee

  • Tennessee Oncology Associates - Nashville

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2010-05
Est. Completion 2015-08
Phase Phase 2

Sponsor

SCRI Development Innovations

146 total trials

What the Registry Record Tells You About NCT01121939

The ClinicalTrials.gov registry entry for NCT01121939 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 278-participant average among 13 other Neuroendocrine Carcinoma trials with a reported enrollment target (85% lower). The listed sponsor is SCRI Development Innovations, which has 146 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Neuroendocrine Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Bevacizumab is the first listed.

NCT01121939 reports 9 study locations spanning 8 distinct geographic areas - top geographies include Florida, Georgia, Kentucky.

Frequently Asked Questions

What is clinical trial NCT01121939 about?

NCT01121939 is a clinical study titled "Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers". The purpose of this Phase II trial will be to define the activity of a VEGF inhibitor bevacizumab, HER1/HER2 inhibitor pertuzumab, and sandostatin for patients with advanced neuroendocrine cancers. In particular, the efficacy of bevacizumab and pertuzumab treatment is of great interest. The prima...

What is the current status of trial NCT01121939?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2010-05. Estimated completion is 2015-08.

What conditions does trial NCT01121939 study?

This clinical trial studies the following conditions: Neuroendocrine Carcinoma.

What interventions are being tested in trial NCT01121939?

The interventions under investigation include: Bevacizumab (DRUG), Pertuzumab (DRUG), Sandostatin LAR® Depot (DRUG).

Who is sponsoring clinical trial NCT01121939?

This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01121939 being conducted?

This trial has 9 study locations across Florida, Georgia, Kentucky, Michigan, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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