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Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers
NCT01121939 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this Phase II trial will be to define the activity of a VEGF inhibitor bevacizumab, HER1/HER2 inhibitor pertuzumab, and sandostatin for patients with advanced neuroendocrine cancers. In particular, the efficacy of bevacizumab and pertuzumab treatment is of great interest. The primary endpoint of this trial will be response rate. Toxicity and progression-free survival will be obtained and evaluated.
Conditions Studied
Interventions
- DRUG Bevacizumab
- DRUG Pertuzumab
- DRUG Sandostatin LAR® Depot
Study Locations (9)
Florida
- Florida Cancer Specialists — Fort Myers
- Florida Hospital Cancer Institute — Orlando
Georgia
- Medical Oncology Associates of Augusta — Augusta
Kentucky
- Baptist Medical Center East — Louisville
Michigan
- Grand Rapids Oncology Program — Grand Rapids
Missouri
- Research Medical Center — Kansas City
New Jersey
- Hematology-Oncology Associates of Northern NJ — Morristown
Ohio
- Oncology Hematology Care, Inc — Cincinnati
Tennessee
- Tennessee Oncology Associates — Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2010-05 |
| Est. Completion | 2015-08 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01121939
The ClinicalTrials.gov registry entry for NCT01121939 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SCRI Development Innovations, which has 63 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Neuroendocrine Carcinoma appearing as the primary indexed condition, and to 3 interventions — of which Bevacizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01121939 reports 9 study locations spanning 8 distinct geographic areas — top geographies include Florida, Georgia, Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01121939 about?
NCT01121939 is a clinical study titled "Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers". The purpose of this Phase II trial will be to define the activity of a VEGF inhibitor bevacizumab, HER1/HER2 inhibitor pertuzumab, and sandostatin for patients with advanced neuroendocrine cancers. In particular, the efficacy of bevacizumab and pertuzumab treatment is of great interest. The prima...
What is the current status of trial NCT01121939?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2010-05. Estimated completion is 2015-08.
What conditions does trial NCT01121939 study?
This clinical trial studies the following conditions: Neuroendocrine Carcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01121939?
The interventions under investigation include: Bevacizumab (DRUG), Pertuzumab (DRUG), Sandostatin LAR® Depot (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01121939?
This trial is sponsored by SCRI Development Innovations, which has 63 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01121939 being conducted?
This trial has 9 study locations across Florida, Georgia, Kentucky, Michigan, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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