Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Multiple Sclerosis (MS) Primary Progressive: full-pipeline trial registry
4 of 4 indexed Multiple Sclerosis (MS) Primary Progressive trials are currently recruiting.
Corpus placement: #4,115 of 28,707 conditions by registered trial count.
4 US clinical trials · 4 currently recruiting · #4,115 of 28,707 conditions by registered trial count
Multiple Sclerosis (MS) Primary Progressive: 4 US clinical trials tracked, 4 recruiting.
Multiple Sclerosis (MS) Primary Progressive is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Tr1X, running 1 of these trials.
Enrollment posture brief
Registry condition multiple-sclerosis-ms-primary-progressive
OPEN 4 | RECR 100% | LATE 1 | EARLY 1 | RANK #4115 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
Multiple Sclerosis (MS) Primary Progressive lists 4 open slots (100% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Multiple Sclerosis (MS) Primary Progressive on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Multiple Sclerosis (MS) Primary Progressive is recruiting above its size-band peers.
4 of 4 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
4 total, page 1 of 1
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Zenas BioPharma (USA)
NCT07067463
"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS
University of California, San Francisco
NCT07222618
Home Based Functional Balance Intervention for Multiple Sclerosis
University of Illinois at Chicago
NCT07355387
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X
NCT07477639
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Multiple Sclerosis (MS) Primary Progressive records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Multiple Sclerosis (MS) Primary Progressive trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Multiple Sclerosis (MS) Primary Progressive page
4 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Multiple Sclerosis (MS) Primary Progressive trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Tr1X sponsors the most Multiple Sclerosis (MS) Primary Progressive trials on record, review their full trial history before evaluating a specific study. See Tr1X's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Multiple Sclerosis (MS) Primary Progressive condition card totals 4 registered trials; most-linked intervention Multicomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance.; top US site state South Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.