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ClinicalTrials.gov 2 recruiting now official registry

Metastatic Malignant Neoplasm clinical trials

Every US clinical trial registered for Metastatic Malignant Neoplasm — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

16 US clinical trials · 2 currently recruiting

The research picture

Metastatic Malignant Neoplasm has 16 registered US clinical trials, 2 of them open to new participants right now — about 13% of the total.

2
recruiting participants now
13%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
12
top sponsor: M.D. Anderson Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 2 1,500 participants

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

Roswell Park Cancer Institute

NCT04068649

RECRUITING Phase 1 144 participants

A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2

NextPoint Therapeutics

NCT06240728

ACTIVE NOT RECRUITING Phase 2 1,362 participants

Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT II)

M.D. Anderson Cancer Center

NCT02152254

ACTIVE NOT RECRUITING NA 406 participants

Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center

M.D. Anderson Cancer Center

NCT03671226

ACTIVE NOT RECRUITING Phase 3 212 participants

A Study of Cancer Related Fatigue in Patients With Metastatic Cancer Receiving Anti-PD1 Immunotherapy

M.D. Anderson Cancer Center

NCT03525873

ACTIVE NOT RECRUITING Phase 2 150 participants

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

M.D. Anderson Cancer Center

NCT02286687

ACTIVE NOT RECRUITING 141 participants

Financial Distress in Advanced Cancer Patients

M.D. Anderson Cancer Center

NCT04053517

ACTIVE NOT RECRUITING Phase 2 110 participants

Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

M.D. Anderson Cancer Center

NCT03743649

ACTIVE NOT RECRUITING Phase 2 90 participants

Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer

M.D. Anderson Cancer Center

NCT02491632

ACTIVE NOT RECRUITING Phase 3 88 participants

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

M.D. Anderson Cancer Center

NCT01592968

ACTIVE NOT RECRUITING Phase 2 70 participants

Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer

M.D. Anderson Cancer Center

NCT03021486

ACTIVE NOT RECRUITING NA 15 participants

Cryoablation for the Treatment of Metastatic Cancer

M.D. Anderson Cancer Center

NCT04150939

COMPLETED 351 participants

Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings

M.D. Anderson Cancer Center

NCT04186884

COMPLETED Phase 3 300 participants

Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism

Academic and Community Cancer Research United

NCT02585713

COMPLETED NA 125 participants

Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits

M.D. Anderson Cancer Center

NCT03856060

COMPLETED Phase 1 12 participants

Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery

University of Chicago

NCT02540876

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 6
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metastatic Malignant Neoplasm Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Metastatic Malignant Neoplasm, and 2 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Metastatic Malignant Neoplasm shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Metastatic Malignant Neoplasm is led by M.D. Anderson Cancer Center with 12 indexed trials, alongside 4 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metastatic Malignant Neoplasm?

PlainTrial tracks 16 US clinical trials for Metastatic Malignant Neoplasm, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metastatic Malignant Neoplasm?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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