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NCT01592968 · ClinicalTrials.gov registry record · Phase 3
Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases
A Phase 3 study of Metastatic Malignant Neoplasm in the Brain and Metastatic Malignant Neoplasm, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 3
- Development phase
- 88
- Enrollment target
- 1
- Study location
NCT01592968: Active Phase 3 study of Metastatic Malignant Neoplasm in the Brain and Metastatic Malignant Neoplasm, sponsored by M.D. Anderson Cancer Center.
NCT01592968 is a Phase 3 study of Metastatic Malignant Neoplasm in the Brain and Metastatic Malignant Neoplasm that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 88 participants, roughly in line with the 86-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01592968, a Phase 3 study of Metastatic Malignant Neoplasm in the Brain and Metastatic Malignant Neoplasm, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 88 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized phase III clinical trial compares stereotactic radiosurgery with whole brain radiation therapy to see how well they work in treating patients with non-melanoma cancer that has recently spread from the first location to the brain. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Stereotactic radiosurgery is a specialized type of radiation therapy that delivers a single, high dose of radiation directly to the tumor and may kill more tumor cells and cause less damage to normal tissue. Whole brain radiation therapy delivers a lower dose of radiation to the entire brain over several treatments. It is not yet known whether stereotactic radiosurgery works better than whole brain radiation therapy in treating patients with non-melanoma brain metastases. Stereotactic radiosurgery may also cause fewer thinking and memory problems than whole brain radiation therapy.
Primary Outcome
Estimated for each treatment arm with 95% confidence intervals based on the estimates of time to local failure.
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- RADIATION Stereotactic Radiosurgery
- OTHER Cognitive Assessment
- RADIATION Whole-Brain Radiotherapy
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2012-08-02 |
| Est. Completion | 2027-09-30 |
| Phase | Phase 3 |
What the registry record for NCT01592968 still lists
NCT01592968 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, roughly in line with the 86-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target.
The record links to 2 conditions, with Metastatic Malignant Neoplasm in the Brain appearing as the primary indexed condition, and to 4 interventions - of which Quality-of-Life Assessment is the first listed.
NCT01592968 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT01592968 about?
NCT01592968 is a clinical study titled "Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases". This randomized phase III clinical trial compares stereotactic radiosurgery with whole brain radiation therapy to see how well they work in treating patients with non-melanoma cancer that has recently spread from the first location to the brain. Radiation therapy uses high energy x-rays to kill tumo...
What is the current status of trial NCT01592968?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 88 participants. The study started on 2012-08-02. Estimated completion is 2027-09-30.
What conditions does trial NCT01592968 study?
This clinical trial studies the following conditions: Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Neoplasm.
What interventions are being tested in trial NCT01592968?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Stereotactic Radiosurgery (RADIATION), Cognitive Assessment (OTHER), Whole-Brain Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT01592968?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01592968 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01592968's enrollment target sits among peer trials
88 16th of 43 higher than 28 of 43 other Metastatic Malignant Neoplasm in the Brain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Malignant Neoplasm in the Brain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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