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NCT02540876 · ClinicalTrials.gov registry record · Phase 1

Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery

A Phase 1 study of Metastatic Malignant Neoplasm and Solid Neoplasm, sponsored by University of Chicago.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT02540876 is a Phase 1 study of Metastatic Malignant Neoplasm and Solid Neoplasm that has completed, run by University of Chicago. The registered enrollment target is 12 participants, below the 338-participant average among 15 other Metastatic Malignant Neoplasm trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02540876, a Phase 1 study of Metastatic Malignant Neoplasm and Solid Neoplasm, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

This pilot phase I trial studies how well ilorasertib works in treating patients with cyclin-dependent kinase inhibitor 2A (CDKN2A)-deficient solid cancers that have spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or have spread to other places in the body (metastatic) and cannot be removed by surgery. Ilorasertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Ilorasertib

Study Locations (1)

Illinois

  • University of Chicago Comprehensive Cancer Center - Chicago

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2015-09-08
Est. Completion 2019-02-08
Phase Phase 1

Sponsor

University of Chicago

796 total trials

What the Registry Record Tells You About NCT02540876

The ClinicalTrials.gov registry entry for NCT02540876 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 338-participant average among 15 other Metastatic Malignant Neoplasm trials with a reported enrollment target (96% lower). The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Metastatic Malignant Neoplasm appearing as the primary indexed condition, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT02540876 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT02540876 about?

NCT02540876 is a clinical study titled "Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery". This pilot phase I trial studies how well ilorasertib works in treating patients with cyclin-dependent kinase inhibitor 2A (CDKN2A)-deficient solid cancers that have spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or have spread to other places ...

What is the current status of trial NCT02540876?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2015-09-08. Estimated completion is 2019-02-08.

What conditions does trial NCT02540876 study?

This clinical trial studies the following conditions: Metastatic Malignant Neoplasm, Solid Neoplasm, Unresectable Malignant Neoplasm.

What interventions are being tested in trial NCT02540876?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Ilorasertib (DRUG).

Who is sponsoring clinical trial NCT02540876?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02540876 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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