Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Melasma: later-stage trial registry
2 of 9 indexed Melasma trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 2 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Melasma: 9 US clinical trials tracked, 2 recruiting.
Melasma is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Sadick Research Group, running 1 of these trials.
Enrollment posture brief
Registry condition melasma
OPEN 2 | RECR 22% | LATE 2 | EARLY 1 | RANK #1916 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acne (22% recruiting · 27 trials)
Melasma lists 2 open slots (22% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Melasma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Melasma is recruiting below its size-band peers.
2 of 9 indexed trials (22.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Melasma trials is spread across many organizations.
Sadick Research Group accounts for 1 of 9 trials (11.1%). 9 distinct sponsors appear on at least one study for this condition label.
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Most Melasma trials plan to enrol fewer than 100 people.
Median target enrolment is 20 among the 9 trials that report a genuine target (sentinel values excluded). 8 of those (88.9%) plan for fewer than 100 participants.
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Melasma research is mostly interventional.
9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
Integrative Skin Science and Research
NCT05942248
Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma
Benev Company
NCT06415435
LaseMD System for the Treatment of Melasma
CynosureLutronic
NCT03456674
Evaluation of an Herbal-Based De-Pigmenting System
Sadick Research Group
NCT02138539
Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women
University of Texas Southwestern Medical Center
NCT00616239
Efficacy and Safety of PiQo4 Device for Treatment of Melasma
Focus Medical
NCT03565341
Topical Composition Therapy (2013-MCN-333) for the Treatment of Melasma
Mayo Clinic
NCT02730819
Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma
Allergan
NCT02977507
A Study of the RevLite Laser System for the Treatment of Refractory Mixed Type Melasma
Cynosure
NCT02110134
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Melasma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Melasma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Melasma page
9 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Melasma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Sadick Research Group sponsors the most Melasma trials on record, review their full trial history before evaluating a specific study. See Sadick Research Group's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Melasma condition card totals 9 registered trials; most-linked intervention Hydroquinone skin care regimen; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.