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2026 data Public-data reference. official source

Malignant Mesothelioma

Open-data reference.

13 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 100 participants

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

InSilico Medicine Hong Kong Limited

NCT06566079

RECRUITING Phase 2 64 participants

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

Memorial Sloan Kettering Cancer Center

NCT06057935

RECRUITING Phase 2 55 participants

Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery

M.D. Anderson Cancer Center

NCT03007030

RECRUITING Phase 1 10 participants

Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease

David Bartlett, MD

NCT07192900

ACTIVE NOT RECRUITING Phase 1 9 participants

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Roswell Park Cancer Institute

NCT03678350

COMPLETED Phase 3 405 participants

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

Alliance for Clinical Trials in Oncology

NCT02349412

COMPLETED Phase 2 69 participants

Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma

Alliance for Clinical Trials in Oncology

NCT00017186

COMPLETED Phase 2 40 participants

Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer

St. Vincent Medical Center - Los Angeles

NCT00002475

COMPLETED Phase 2 30 participants

Liposomal-Cisplatin Analogue (L-NDDP) in Treating Patients With Malignant Pleural Mesothelioma

NYU Langone Health

NCT00004033

COMPLETED Phase 2 30 participants

Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer

Jonsson Comprehensive Cancer Center

NCT00024076

COMPLETED Phase 1 20 participants

Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage IIIA Non-small Cell Lung Cancer or With Stage I or Stage II Mesothelioma

Roswell Park Cancer Institute

NCT00003974

COMPLETED Phase 1 6 participants

Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

Fox Chase Cancer Center

NCT00003263

COMPLETED Phase 3

Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery

Memorial Sloan Kettering Cancer Center

NCT00005636

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 6
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Malignant Mesothelioma Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Malignant Mesothelioma, and 4 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Malignant Mesothelioma shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Malignant Mesothelioma is led by Alliance for Clinical Trials in Oncology with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Malignant Mesothelioma?

PlainTrial tracks 13 US clinical trials for Malignant Mesothelioma, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Malignant Mesothelioma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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