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ClinicalTrials.gov 4 recruiting now official registry

Lung Cancer, Non-Small Cell clinical trials

4 of 11 indexed Lung Cancer, Non-Small Cell trials are currently recruiting.

11 US clinical trials · 4 currently recruiting

Lung Cancer, Non-Small Cell is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 5 of these trials.

The research picture

Lung Cancer, Non-Small Cell has 11 registered US clinical trials, 4 of them open to new participants right now, about 36% of the total.

4
recruiting participants now
36%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
5
top sponsor: GlaxoSmithKline
Phase 12Phase 22Phase 34

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 1 250 participants

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Krystal Biotech

NCT06228326

RECRUITING NA 194 participants

Engagement of Veterans With Lung Cancer

Palo Alto Veterans Institute for Research

NCT07219251

RECRUITING Phase 1 150 participants

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

MBrace Therapeutics

NCT07145255

RECRUITING 20 participants

Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

Our Lady of the Lake Hospital

NCT06659458

ACTIVE NOT RECRUITING Phase 3 758 participants

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

GlaxoSmithKline

NCT04655976

ACTIVE NOT RECRUITING Phase 3 666 participants

Placebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung Cancer

GlaxoSmithKline

NCT04475939

ACTIVE NOT RECRUITING Phase 2 351 participants

A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer

GlaxoSmithKline

NCT05565378

ACTIVE NOT RECRUITING NA 299 participants

NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

Tufts University

NCT04986670

ACTIVE NOT RECRUITING Phase 3 88 participants

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

GlaxoSmithKline

NCT06472076

ACTIVE NOT RECRUITING Phase 2 63 participants

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

IO Biotech

NCT05077709

COMPLETED Phase 3 472 participants

Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer

GlaxoSmithKline

NCT00390806

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lung Cancer, Non-Small Cell Trial Landscape

11 indexed Lung Cancer, Non-Small Cell studies · 4 recruiting (36%).

Phase mix: 4 late (III/IV) vs 4 early (I/II).

Top sponsor: GlaxoSmithKline (5 trials), 6 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lung Cancer, Non-Small Cell?

PlainTrial tracks 11 US clinical trials for Lung Cancer, Non-Small Cell, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lung Cancer, Non-Small Cell?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.