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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Lung Cancer, Non-Small Cell: early-phase trial registry

7 of 17 indexed Lung Cancer, Non-Small Cell trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 7 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Lung Cancer, Non-Small Cell: 17 US clinical trials tracked, 7 recruiting.

Lung Cancer, Non-Small Cell is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 5 of these trials.

Enrollment posture brief

Registry condition lung-cancer-non-small-cell

OPEN 7 | RECR 41% | LATE 4 | EARLY 7 | RANK #1004 | SPON 5

Nearest open-share peer: Erectile Dysfunction (41% recruiting · 34 trials)

Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Lung Cancer, Non-Small C (th…41%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Lung Cancer, Non-Small Cell

Lung Cancer, Non-Small Cell lists 7 open slots (41% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lung Cancer, Non-Small Cell on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lung Cancer, Non-Small Cell is recruiting below its size-band peers.

    7 of 17 indexed trials (41.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Lung Cancer, Non-Small Cell research.

    GlaxoSmithKline accounts for 5 of 17 trials (29.4%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Lung Cancer, Non-Small Cell enrolment sits around 194 participants.

    Median target enrolment is 194 among the 17 trials that report a genuine target (sentinel values excluded). 7 of those (41.2%) plan for fewer than 100 participants.

  4. Lung Cancer, Non-Small Cell research is mostly interventional.

    13 interventional and 4 observational studies make up this index (76.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 23Phase 34

Open and recent trials

17 total, page 1 of 1

RECRUITING 2,200 participants

I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

NCT05537922

RECRUITING 1,650 participants

A Multicenter Cancer Biospecimen Collection Study

Cofactor Genomics

NCT04510129

RECRUITING Phase 1 250 participants

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Krystal Biotech

NCT06228326

RECRUITING NA 194 participants

Engagement of Veterans With Lung Cancer

Palo Alto Veterans Institute for Research

NCT07219251

RECRUITING Phase 1 150 participants

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

MBrace Therapeutics

NCT07145255

RECRUITING Phase 1 28 participants

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

Abramson Cancer Center at Penn Medicine

NCT04691817

RECRUITING 20 participants

Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

Our Lady of the Lake Hospital

NCT06659458

ACTIVE NOT RECRUITING Phase 3 758 participants

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

GlaxoSmithKline

NCT04655976

ACTIVE NOT RECRUITING Phase 3 666 participants

Placebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung Cancer

GlaxoSmithKline

NCT04475939

ACTIVE NOT RECRUITING Phase 2 351 participants

A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer

GlaxoSmithKline

NCT05565378

ACTIVE NOT RECRUITING NA 299 participants

NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

Tufts University

NCT04986670

ACTIVE NOT RECRUITING Phase 3 88 participants

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

GlaxoSmithKline

NCT06472076

ACTIVE NOT RECRUITING Phase 1 66 participants

Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03377023

ACTIVE NOT RECRUITING Phase 2 63 participants

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

IO Biotech

NCT05077709

ACTIVE NOT RECRUITING 23 participants

Immune Signature Analysis of Disease Progression in Post Immunotherapy Lung Cancer Patients

Wake Forest University Health Sciences

NCT05415358

COMPLETED Phase 3 472 participants

Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer

GlaxoSmithKline

NCT00390806

COMPLETED Phase 2 5 participants

Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.

Seagen

NCT03245736

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 3
Phase 3 4

Named interventions

Most-linked intervention names on Lung Cancer, Non-Small Cell records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Dostarlimab Biological
2 trials
Docetaxel Drug
2 trials
Placebo Drug
2 trials
Pembrolizumab Biological
2 trials
HYCAMTIN, oral capsules Drug
1 trials
Tisotumab Vedotin Drug
1 trials
Blood and tissue samples Other
1 trials
Cobolimab Biological
1 trials

US sites by state

Facility locations filed on Lung Cancer, Non-Small Cell trials. A trial with sites in several states counts in each.

Florida 8 trials
California 8 trials
Texas 6 trials
Pennsylvania 6 trials
Tennessee 4 trials
Virginia 3 trials
Ohio 3 trials
New York 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lung Cancer, Non-Small Cell page

17 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Lung Cancer, Non-Small Cell trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • GlaxoSmithKline sponsors the most Lung Cancer, Non-Small Cell trials on record, review their full trial history before evaluating a specific study. See GlaxoSmithKline's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lung Cancer, Non-Small Cell condition card totals 17 registered trials; most-linked intervention Dostarlimab; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.