Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Locally Advanced Lung Non-Small Cell Carcinoma: early-phase trial registry

5 of 9 indexed Locally Advanced Lung Non-Small Cell Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 5 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Locally Advanced Lung Non-Small Cell Carcinoma: 9 US clinical trials tracked, 5 recruiting.

Locally Advanced Lung Non-Small Cell Carcinoma is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition locally-advanced-lung-non-small-cell-carcinoma

OPEN 5 | RECR 56% | LATE 1 | EARLY 6 | RANK #1916 | SPON 3

Nearest open-share peer: Advanced Colorectal Cancer (56% recruiting · 9 trials)

Locally Advanced Lung No (th…56%Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Locally Advanced Lung Non-Small Cell Carcinoma

Locally Advanced Lung Non-Small Cell Carcinoma lists 5 open slots (56% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Locally Advanced Lung Non-Small Cell Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Locally Advanced Lung Non-Small Cell Carcinoma is recruiting above its size-band peers.

    5 of 9 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Locally Advanced Lung Non-Small Cell Carcinoma research.

    M.D. Anderson Cancer Center accounts for 3 of 9 trials (33.3%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Most Locally Advanced Lung Non-Small Cell Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 34 among the 9 trials that report a genuine target (sentinel values excluded). 7 of those (77.8%) plan for fewer than 100 participants.

  4. Locally Advanced Lung Non-Small Cell Carcinoma research is mostly interventional.

    9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 21Phase 31

Open and recent trials

9 total, page 1 of 1

RECRUITING Phase 3 474 participants

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

NRG Oncology

NCT05624996

RECRUITING NA 100 participants

Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation

M.D. Anderson Cancer Center

NCT05010109

RECRUITING Phase 1 37 participants

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

National Cancer Institute (NCI)

NCT07012031

RECRUITING NA 34 participants

Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer

Rutgers, The State University of New Jersey

NCT04751747

RECRUITING Phase 1 28 participants

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

Ohio State University Comprehensive Cancer Center

NCT05136846

ACTIVE NOT RECRUITING Phase 2 35 participants

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

M.D. Anderson Cancer Center

NCT04940299

ACTIVE NOT RECRUITING Phase 1 21 participants

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

M.D. Anderson Cancer Center

NCT04013542

ACTIVE NOT RECRUITING Phase 1 8 participants

Minnelide and Osimertinib for the Treatment of Advanced EGFR Mutated Non-Small Cell Lung Cancer

City of Hope Medical Center

NCT05166616

ACTIVE NOT RECRUITING Phase 1 5 participants

Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC

City of Hope Medical Center

NCT04227028

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 1
Phase 3 1

Named interventions

Most-linked intervention names on Locally Advanced Lung Non-Small Cell Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
4 trials
Ipilimumab Biological
2 trials
Nivolumab Biological
2 trials
Radiation Therapy Radiation
2 trials
Durvalumab Biological
2 trials
Biospecimen Collection Procedure
2 trials
Carboplatin Drug
2 trials
Triptolide Analog Drug
1 trials

US sites by state

Facility locations filed on Locally Advanced Lung Non-Small Cell Carcinoma trials. A trial with sites in several states counts in each.

California 4 trials
Texas 3 trials
Wisconsin 1 trials
Pennsylvania 1 trials
Ohio 1 trials
New Jersey 1 trials
Illinois 1 trials
Florida 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Locally Advanced Lung Non-Small Cell Carcinoma page

9 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Locally Advanced Lung Non-Small Cell Carcinoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • M.D. Anderson Cancer Center sponsors the most Locally Advanced Lung Non-Small Cell Carcinoma trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Locally Advanced Lung Non-Small Cell Carcinoma condition card totals 9 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.