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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Knee Arthroplasty, Total: early-phase trial registry

2 of 4 indexed Knee Arthroplasty, Total trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4,115 of 28,707 conditions by registered trial count.

4 US clinical trials · 2 currently recruiting · #4,115 of 28,707 conditions by registered trial count

Knee Arthroplasty, Total: 4 US clinical trials tracked, 2 recruiting.

Knee Arthroplasty, Total is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Exactech, running 2 of these trials.

Enrollment posture brief

Registry condition knee-arthroplasty-total

OPEN 2 | RECR 50% | LATE 0 | EARLY 1 | RANK #4115 | SPON 2

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Ablation80%ACL Reconstruction80%Abuse, Drug60%Acceptability60%Knee Arthroplasty, Total (th…50%
Open-enrollment share among volume-matched conditions near Knee Arthroplasty, Total

Knee Arthroplasty, Total lists 2 open slots (50% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Knee Arthroplasty, Total on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Knee Arthroplasty, Total is recruiting above its size-band peers.

    2 of 4 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Phase 11

Phase Distribution

PhaseTrial count
Phase 1 1

Top Sponsors

Named interventions

Most-linked intervention names on Knee Arthroplasty, Total records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Optetrak Total Knee System Device
1 trials
LEGION Hinge Knee System Device
1 trials
Placebo - Losartan Drug
1 trials
Truliant Total Knee System Device
1 trials
Losartan Drug
1 trials

US sites by state

Facility locations filed on Knee Arthroplasty, Total trials. A trial with sites in several states counts in each.

South Carolina 2 trials
Nevada 2 trials
Colorado 2 trials
Oregon 1 trials
Ohio 1 trials
New York 1 trials
Massachusetts 1 trials
Iowa 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Knee Arthroplasty, Total page

4 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Knee Arthroplasty, Total trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Exactech sponsors the most Knee Arthroplasty, Total trials on record, review their full trial history before evaluating a specific study. See Exactech's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Knee Arthroplasty, Total condition card totals 4 registered trials; most-linked intervention Optetrak Total Knee System; top US site state South Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.