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NCT06108063 · ClinicalTrials.gov registry record · Phase 1
Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan
A Phase 1 study of Knee Arthroplasty, Total, sponsored by Steadman Philippon Research Institute.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06108063: Recruiting Phase 1 study of Knee Arthroplasty, Total, sponsored by Steadman Philippon Research Institute.
NCT06108063 is a Phase 1 study of Knee Arthroplasty, Total that is actively recruiting participants, run by Steadman Philippon Research Institute. The registered enrollment target is 120 participants, below the 1,878-participant average among 3 other Knee Arthroplasty, Total trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06108063, a Phase 1 study of Knee Arthroplasty, Total, is actively recruiting participants, sponsored by Steadman Philippon Research Institute.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the efficacy of Losartan use post-operatively for reducing or preventing the development of arthrofibrosis and the associated adverse impacts on clinical outcomes.
Primary Outcome
Thickness of knee joint capsule will be measured using quantitative ultrasound. The thickness will be measured using the distance between the two bright echoes seen on the ultrasound image that correspond to the superficial and deep edges of the capsule.
Conditions Studied
Interventions
- DRUG Losartan
- DRUG Placebo - Losartan
Study Locations (1)
Colorado
- The Steadman Clinic - Vail
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2024-03-06 |
| Est. Completion | 2027-06-30 |
| Phase | Phase 1 |
What NCT06108063 shows while recruiting
NCT06108063 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 1,878-participant average among 3 other Knee Arthroplasty, Total trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Knee Arthroplasty, Total appearing as the primary indexed condition, and to 2 interventions - of which Losartan is the first listed.
NCT06108063 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT06108063 about?
NCT06108063 is a clinical study titled "Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan". The purpose of this study is to evaluate the efficacy of Losartan use post-operatively for reducing or preventing the development of arthrofibrosis and the associated adverse impacts on clinical outcomes.
What is the current status of trial NCT06108063?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2024-03-06. Estimated completion is 2027-06-30.
What conditions does trial NCT06108063 study?
This clinical trial studies the following conditions: Knee Arthroplasty, Total.
What interventions are being tested in trial NCT06108063?
The interventions under investigation include: Losartan (DRUG), Placebo - Losartan (DRUG).
Who is sponsoring clinical trial NCT06108063?
This trial is sponsored by Steadman Philippon Research Institute, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06108063 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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