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ClinicalTrials.gov 3 recruiting now official registry

Intermittent Claudication clinical trials

3 of 12 indexed Intermittent Claudication trials are currently recruiting.

12 US clinical trials · 3 currently recruiting

Intermittent Claudication is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.

The research picture

Intermittent Claudication has 12 registered US clinical trials, 3 of them open to new participants right now, about 25% of the total.

3
recruiting participants now
25%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Northwestern University
Phase 11Phase 24Phase 32

Active & Recent Trials

12 total, page 1 of 1

RECRUITING Phase 3 386 participants

Improving Mobility After Revascularization in Peripheral Artery Disease

Northwestern University

NCT06686121

RECRUITING Phase 2 200 participants

Response to Exercise and Nitric Oxide in PAD

Northwestern University

NCT06657976

RECRUITING Phase 3 200 participants

MetfOrmin BenefIts Lower Extremities With Intermittent Claudication

VA Office of Research and Development

NCT05132439

ACTIVE NOT RECRUITING NA 333 participants

The Chocolate Touch Study

TriReme Medical

NCT02924857

COMPLETED Phase 2 553 participants

Efficacy and Safety of HMR1766 in Patients With Fontaine Stage II Peripheral Arterial Disease

Sanofi

NCT00443287

COMPLETED Phase 2 289 participants

Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication

Genzyme, a Sanofi Company

NCT00117650

COMPLETED Phase 2 190 participants

A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease

BioMarin Pharmaceutical

NCT00403494

COMPLETED 100 participants

Distributed Registry

Stanford University

NCT03898570

COMPLETED NA 50 participants

Exercise Training for Patients With Poor Leg Circulation

US Department of Veterans Affairs

NCT00118560

COMPLETED NA 32 participants

Bioequivalency Study of 100 mg Cilostazol Tablets Under Fasting Conditions

Roxane Laboratories

NCT00602173

COMPLETED NA 24 participants

Ischemic Preconditioning Claudication Study

Medical College of Wisconsin

NCT03511157

COMPLETED Phase 1 21 participants

Pharmacokinetic Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers

Genovate Biotechnology Co., Ltd.,

NCT03480321

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Intermittent Claudication Trial Landscape

12 indexed Intermittent Claudication studies · 3 recruiting (25%).

Phase mix: 2 late (III/IV) vs 5 early (I/II).

Top sponsor: Northwestern University (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Intermittent Claudication?

PlainTrial tracks 12 US clinical trials for Intermittent Claudication, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Intermittent Claudication?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.