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Human Immunodeficiency Virus (HIV) clinical trials
Every US clinical trial registered for Human Immunodeficiency Virus (HIV) — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
19 US clinical trials · 7 currently recruiting
The research picture
Human Immunodeficiency Virus (HIV) has 19 registered US clinical trials, 7 of them open to new participants right now — about 37% of the total.
- 7
- recruiting participants now
- 37%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 2
- top sponsor: AbbVie
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Merck Sharp & Dohme
NCT07044297
Persuasive Health Communication Intervention for HIV/HCV
Icahn School of Medicine at Mount Sinai
NCT05968573
Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
New York University
NCT06598397
Quitting Matters Human Immunodeficiency Virus Hybrid Trial
Wake Forest University Health Sciences
NCT06883097
e-HERO: Ending the HIV Epidemic in Rural Oklahoma
Northern Arizona University
NCT05664802
Project neuroARTEMIS
Wake Forest University Health Sciences
NCT06814275
The Trans-Led Care Study
Illinois Institute of Technology
NCT06880705
Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk
April M Young
NCT05657106
New Strategies to Assess Anal Cancer Risk In Women
Emory University
NCT02873741
Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis
PATH
NCT02165202
Evaluating Rewards-Based Adherence and Electronic Medication Monitoring in HIV-Positive Adolescents
St. Jude Children's Research Hospital
NCT01849393
Safety, Tolerability, and Immunogenicity of ALFQ in a HIV Vaccine Containing A244 and B.65321 in Healthy Adults
U.S. Army Medical Research and Development Command
NCT05423418
Tesamorelin Effects on Liver Fat and Histology in HIV
Massachusetts General Hospital
NCT02196831
Study to Assess Adverse Events and How Intravenous (IV) or Subcutaneous (SC) ABBV-382 Moves Through the Body of Adult Participants With Human Immuno-Deficiency Virus (HIV-1)
AbbVie
NCT04554966
Romidepsin Plus 3BNC117 Phase 2a Study
Rockefeller University
NCT02850016
A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1
AbbVie
NCT04223804
A Study to Assess the Acceptability of the Darunavir/Cobicistat (DRV/COBI) Fixed-dose Combination (FDC) Tablet in Human Immunodeficiency Virus (HIV)-1 Infected Children
Janssen Research & Development
NCT05197075
A Drug-Drug Interaction Study of MK 8527 With a Combined Oral Contraceptive (LNG/EE)
Merck Sharp & Dohme
NCT06783192
Effect of Seminal Fluid on the Colon Wall; Implications for HIV Transmission
Johns Hopkins University
NCT01053741
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Human Immunodeficiency Virus (HIV) Trial Landscape
ClinicalTrials.gov lists 19 US studies indexed under Human Immunodeficiency Virus (HIV), and 7 of those are currently open to recruitment — roughly 37% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Human Immunodeficiency Virus (HIV) shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Human Immunodeficiency Virus (HIV) is led by AbbVie with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Human Immunodeficiency Virus (HIV)?
PlainTrial tracks 19 US clinical trials for Human Immunodeficiency Virus (HIV), of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Human Immunodeficiency Virus (HIV)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.