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HPV-Related Squamous Cell Carcinoma: early-phase trial registry
4 of 7 indexed HPV-Related Squamous Cell Carcinoma trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 4 currently recruiting · #2,497 of 28,707 conditions by registered trial count
HPV-Related Squamous Cell Carcinoma: 7 US clinical trials tracked, 4 recruiting.
HPV-Related Squamous Cell Carcinoma is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Jonathan Schoenfeld, MD, MPH, running 1 of these trials.
Enrollment posture brief
Registry condition hpv-related-squamous-cell-carcinoma
OPEN 4 | RECR 57% | LATE 1 | EARLY 6 | RANK #2497 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adverse Childhood Experiences (57% recruiting · 14 trials)
HPV-Related Squamous Cell Carcinoma lists 4 open slots (57% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for HPV-Related Squamous Cell Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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HPV-Related Squamous Cell Carcinoma is recruiting above its size-band peers.
4 of 7 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of HPV-Related Squamous Cell Carcinoma trials is spread across many organizations.
Jonathan Schoenfeld, MD, MPH accounts for 1 of 7 trials (14.3%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical HPV-Related Squamous Cell Carcinoma enrolment sits around 35 participants.
Median target enrolment is 35 among the 7 trials that report a genuine target (sentinel values excluded). 4 of those (57.1%) plan for fewer than 100 participants.
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HPV-Related Squamous Cell Carcinoma research is mostly interventional.
7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer
Memorial Sloan Kettering Cancer Center
NCT06563479
Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study
Jonathan Schoenfeld, MD, MPH
NCT04900623
Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04988074
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
Christian Hinrichs
NCT05639972
A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors
TScan Therapeutics
NCT05973487
HPV-16 Vaccination and Pembrolizumab Plus Cisplatin for "Intermediate Risk" HPV-16-associated Head and Neck Squamous Cell Carcinoma
Dan Zandberg
NCT04369937
De-Escalation Therapy for Human Papillomavirus Negative Disease
University of Chicago
NCT03944915
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on HPV-Related Squamous Cell Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on HPV-Related Squamous Cell Carcinoma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this HPV-Related Squamous Cell Carcinoma page
7 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 HPV-Related Squamous Cell Carcinoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Jonathan Schoenfeld, MD, MPH sponsors the most HPV-Related Squamous Cell Carcinoma trials on record, review their full trial history before evaluating a specific study. See Jonathan Schoenfeld, MD, MPH's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This HPV-Related Squamous Cell Carcinoma condition card totals 7 registered trials; most-linked intervention Hydroxyurea Pill; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.