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ClinicalTrials.gov 8 recruiting now official registry

High-risk Neuroblastoma clinical trials

8 of 10 indexed High-risk Neuroblastoma trials are currently recruiting.

10 US clinical trials · 8 currently recruiting

High-risk Neuroblastoma is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Stephan Grupp MD PhD, running 2 of these trials.

The research picture

High-risk Neuroblastoma has 10 registered US clinical trials, 8 of them open to new participants right now, about 80% of the total.

8
recruiting participants now
80%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Stephan Grupp MD PhD
Phase 14Phase 24

Active & Recent Trials

10 total, page 1 of 1

RECRUITING Phase 2 94 participants

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT06057948

RECRUITING NA 84 participants

Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

Dana-Farber Cancer Institute

NCT06831552

RECRUITING Phase 1 60 participants

GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

Y-mAbs Therapeutics

NCT05130255

RECRUITING 45 participants

Feasibility of Screening for Early Late Effects of Contemporary Therapy in High-Risk Neuroblastoma Survivors

St. Jude Children's Research Hospital

NCT06480526

RECRUITING Phase 1 45 participants

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

Stephan Grupp MD PhD

NCT05650749

RECRUITING Phase 2 45 participants

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT06528496

RECRUITING Phase 1 42 participants

Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

Roberto Chiarle

NCT06803875

RECRUITING Phase 1 38 participants

PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma

Stephan Grupp MD PhD

NCT07007117

ACTIVE NOT RECRUITING Phase 2 94 participants

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Children's Oncology Group

NCT03794349

ACTIVE NOT RECRUITING Phase 2 42 participants

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

National Cancer Institute (NCI)

NCT03786783

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the High-risk Neuroblastoma Trial Landscape

10 indexed High-risk Neuroblastoma studies · 8 recruiting (80%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: Stephan Grupp MD PhD (2 trials), 7 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for High-risk Neuroblastoma?

PlainTrial tracks 10 US clinical trials for High-risk Neuroblastoma, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for High-risk Neuroblastoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.