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Heart Valve Diseases
Open-data reference.
14 US clinical trials · 6 currently recruiting
Active & Recent Trials
Transpacific TAVR Registry
Duk-Woo Park, MD
NCT03826264
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
University of California, San Francis
NCT05933083
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
Cardiac Dimensions
NCT03142152
Warfarin Patient Self-management Implementation in the US Healthcare System
University of Utah
NCT04766216
The TRICURE EFS Study
TRiCares
NCT06506942
EFS of the DUO System for Tricuspid Regurgitation
CroiValve Limited
NCT05913908
TRISCEND II Pivotal Trial
Edwards Lifesciences
NCT04482062
2019-06 TRISCEND Study
Edwards Lifesciences
NCT04221490
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Abbott Medical Devices
NCT03433274
Paired-Ring Mitral Annuloplasty Ring Sizing Device
Endeavor Health
NCT06965725
A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System
GE Healthcare
NCT01076296
Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve
Sorin Group USA
NCT00630916
Medtronic HAMMOCK Post Approval Study
Medtronic Cardiac Surgery
NCT03139721
Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
Abbott Medical Devices
NCT03539458
Phase Distribution
Phase data not available
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Heart Valve Diseases Trial Landscape
ClinicalTrials.gov lists 14 US studies indexed under Heart Valve Diseases, and 6 of those are currently open to recruitment — roughly 43% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Heart Valve Diseases shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Heart Valve Diseases is led by Edwards Lifesciences with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Heart Valve Diseases?
PlainTrial tracks 14 US clinical trials for Heart Valve Diseases, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Heart Valve Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.