Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 6 recruiting now official registry

Heart Valve Diseases clinical trials

6 of 14 indexed Heart Valve Diseases trials are currently recruiting.

14 US clinical trials · 6 currently recruiting

Heart Valve Diseases is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. The most active sponsor is Edwards Lifesciences, running 2 of these trials.

The research picture

Heart Valve Diseases has 14 registered US clinical trials, 6 of them open to new participants right now, about 43% of the total.

6
recruiting participants now
43%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Edwards Lifesciences

Active & Recent Trials

14 total, page 1 of 1

RECRUITING 10,000 participants

Transpacific TAVR Registry

Duk-Woo Park, MD

NCT03826264

RECRUITING NA 516 participants

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

University of California, San Francisco

NCT05933083

RECRUITING NA 300 participants

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Cardiac Dimensions

NCT03142152

RECRUITING NA 150 participants

Warfarin Patient Self-management Implementation in the US Healthcare System

University of Utah

NCT04766216

RECRUITING NA 15 participants

The TRICURE EFS Study

TRiCares

NCT06506942

RECRUITING NA 15 participants

EFS of the DUO System for Tricuspid Regurgitation

CroiValve Limited

NCT05913908

ACTIVE NOT RECRUITING NA 864 participants

TRISCEND II Pivotal Trial

Edwards Lifesciences

NCT04482062

ACTIVE NOT RECRUITING NA 228 participants

2019-06 TRISCEND Study

Edwards Lifesciences

NCT04221490

ACTIVE NOT RECRUITING NA 103 participants

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Abbott Medical Devices

NCT03433274

ACTIVE NOT RECRUITING 22 participants

Paired-Ring Mitral Annuloplasty Ring Sizing Device

Endeavor Health

NCT06965725

COMPLETED 1,000 participants

A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System

GE Healthcare

NCT01076296

COMPLETED NA 756 participants

Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve

Sorin Group USA

NCT00630916

COMPLETED 122 participants

Medtronic HAMMOCK Post Approval Study

Medtronic Cardiac Surgery

NCT03139721

COMPLETED NA 11 participants

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Abbott Medical Devices

NCT03539458

Phase Distribution

Phase data not available

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Heart Valve Diseases Trial Landscape

14 indexed Heart Valve Diseases studies · 6 recruiting (43%).

Phase mix: 0 late (III/IV) vs 0 early (I/II).

Top sponsor: Edwards Lifesciences (2 trials), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Heart Valve Diseases?

PlainTrial tracks 14 US clinical trials for Heart Valve Diseases, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Heart Valve Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.