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ClinicalTrials.gov 6 recruiting now small index

Heart Valve Diseases clinical trials

6 of 14 indexed Heart Valve Diseases trials are currently recruiting.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 6 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Heart Valve Diseases: 14 US clinical trials tracked, 6 recruiting.

Heart Valve Diseases is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. The most active sponsor is Edwards Lifesciences, running 2 of these trials.

Enrollment posture brief

Registry condition heart-valve-diseases

OPEN 6 | RECR 43% | LATE 0 | EARLY 0 | RANK #1230 | SPON 2

Nearest open-share peer: Acute Myelogenous Leukemia (AML) (43% recruiting · 7 trials)

Heart Valve Diseases (this)43%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Heart Valve Diseases

Heart Valve Diseases lists 6 open slots (43% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Heart Valve Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Heart Valve Diseases is recruiting below its size-band peers.

    6 of 14 indexed trials (42.9%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Heart Valve Diseases trials is spread across many organizations.

    Edwards Lifesciences accounts for 2 of 14 trials (14.3%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Heart Valve Diseases enrolment sits around 228 participants.

    Median target enrolment is 228 among the 14 trials that report a genuine target (sentinel values excluded). 4 of those (28.6%) plan for fewer than 100 participants.

  4. Heart Valve Diseases research is mostly interventional.

    10 interventional and 4 observational studies make up this index (71.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Open and recent trials

14 total, page 1 of 1

RECRUITING 10,000 participants

Transpacific TAVR Registry

Duk-Woo Park, MD

NCT03826264

RECRUITING NA 516 participants

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

University of California, San Francisco

NCT05933083

RECRUITING NA 300 participants

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Cardiac Dimensions

NCT03142152

RECRUITING NA 150 participants

Warfarin Patient Self-management Implementation in the US Healthcare System

University of Utah

NCT04766216

RECRUITING NA 15 participants

The TRICURE EFS Study

TRiCares

NCT06506942

RECRUITING NA 15 participants

EFS of the DUO System for Tricuspid Regurgitation

CroiValve Limited

NCT05913908

ACTIVE NOT RECRUITING NA 864 participants

TRISCEND II Pivotal Trial

Edwards Lifesciences

NCT04482062

ACTIVE NOT RECRUITING NA 228 participants

2019-06 TRISCEND Study

Edwards Lifesciences

NCT04221490

ACTIVE NOT RECRUITING NA 103 participants

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Abbott Medical Devices

NCT03433274

ACTIVE NOT RECRUITING 22 participants

Paired-Ring Mitral Annuloplasty Ring Sizing Device

Endeavor Health

NCT06965725

COMPLETED 1,000 participants

A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System

GE Healthcare

NCT01076296

COMPLETED NA 756 participants

Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve

Sorin Group USA

NCT00630916

COMPLETED 122 participants

Medtronic HAMMOCK Post Approval Study

Medtronic Cardiac Surgery

NCT03139721

COMPLETED NA 11 participants

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Abbott Medical Devices

NCT03539458

Phase Distribution

Phase data not available

Named interventions

Most-linked intervention names on Heart Valve Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Tendyne Mitral Valve System Device
2 trials
Transcatheter Tricuspid Valve Replacement Device
2 trials
Mitroflow Aortic Heart Valve Device
1 trials
Mosaic model 305, model 310, and ultra model 305 Device
1 trials
Annuloplasy ring sizing device Device
1 trials
MitraClip System Device
1 trials
Edwards EVOQUE System Device
1 trials
DUO Transcatheter Tricuspid Coaptation Valve System Device
1 trials

US sites by state

Facility locations filed on Heart Valve Diseases trials. A trial with sites in several states counts in each.

California 9 trials
Illinois 6 trials
Georgia 6 trials
Arizona 5 trials
Pennsylvania 4 trials
New York 4 trials
Minnesota 4 trials
Michigan 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Heart Valve Diseases page

14 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heart Valve Diseases condition card totals 14 registered trials; most-linked intervention Tendyne Mitral Valve System; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.