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ClinicalTrials.gov 12 recruiting now official registry

Glioblastoma, IDH-wildtype clinical trials

12 of 16 indexed Glioblastoma, IDH-wildtype trials are currently recruiting.

16 US clinical trials · 12 currently recruiting

Glioblastoma, IDH-wildtype is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Jasper Gerritsen, running 4 of these trials.

The research picture

Glioblastoma, IDH-wildtype has 16 registered US clinical trials, 12 of them open to new participants right now, about 75% of the total.

12
recruiting participants now
75%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: Jasper Gerritsen
Phase 16Phase 23Phase 31

Active & Recent Trials

16 total, page 1 of 1

RECRUITING 1,015 participants

The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)

Jasper Gerritsen

NCT06146738

RECRUITING 784 participants

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

Jasper Gerritsen

NCT06118723

RECRUITING 564 participants

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

Jasper Gerritsen

NCT06146725

RECRUITING 464 participants

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

Jasper Gerritsen

NCT06283927

RECRUITING Phase 3 432 participants

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Northwell Health

NCT05271240

RECRUITING 225 participants

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Erasmus Medical Center

NCT06273176

RECRUITING Phase 1 134 participants

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Neonc Technologies

NCT06047379

RECRUITING NA 116 participants

Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma

Mayo Clinic

NCT07091864

RECRUITING Phase 2 100 participants

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

ECOG-ACRIN Cancer Research Group

NCT06319027

RECRUITING Phase 1 66 participants

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

Orbus Therapeutics

NCT05879367

RECRUITING Phase 2 39 participants

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Northwestern University

NCT05879250

RECRUITING Phase 1 20 participants

A Study of 177Lu-PSMA-617 in People With Gliomas

Memorial Sloan Kettering Cancer Center

NCT07223034

ACTIVE NOT RECRUITING Phase 1 60 participants

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Northwestern University

NCT05236036

ACTIVE NOT RECRUITING Phase 1 57 participants

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

Northwestern University

NCT04528680

ACTIVE NOT RECRUITING Phase 1 56 participants

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Mayo Clinic

NCT04197934

ACTIVE NOT RECRUITING Phase 2 37 participants

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

National Cancer Institute (NCI)

NCT04145115

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Glioblastoma, IDH-wildtype Trial Landscape

16 indexed Glioblastoma, IDH-wildtype studies · 12 recruiting (75%).

Phase mix: 1 late (III/IV) vs 9 early (I/II).

Top sponsor: Jasper Gerritsen (4 trials), 9 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Glioblastoma, IDH-wildtype?

PlainTrial tracks 16 US clinical trials for Glioblastoma, IDH-wildtype, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Glioblastoma, IDH-wildtype?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.