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First Episode Psychosis clinical trials
7 of 9 indexed First Episode Psychosis trials are currently recruiting.
9 US clinical trials · 7 currently recruiting
First Episode Psychosis is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Northwell Health, running 3 of these trials.
The research picture
First Episode Psychosis has 9 registered US clinical trials, 7 of them open to new participants right now, about 78% of the total.
- 7
- recruiting participants now
- 78%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Northwell Health
Active & Recent Trials
9 total, page 1 of 1
Digital Strategies to Advance Help-Seeking Aim 1 and 2
Columbia University
NCT06774430
Digital Strategies to Advance Help-Seeking - Aim 3
Columbia University
NCT06774417
Early-Phase Schizophrenia: Practice-based Research to Improve Outcomes
Northwell Health
NCT04004364
Disengagement in CSC: Identifying Those at Risk and Addressing Their Needs
Northwell Health
NCT04005378
Artificial Intelligence to Measure Adherence to Oral Medication
Northwell Health
NCT04046497
Pilot RCT of Self-stigma Treatment for First Episode Psychosis
John Jay College of Criminal Justice, City University of New York
NCT04889911
Normobaric Oxygen Therapy for Individuals With First-Episode Psychosis
Nicholas Breitborde
NCT04368039
Trial to Increase FEP Attendance
University of Pennsylvania
NCT05967195
Optimizing Engagement in Services for First-Episode Psychosis
California State University, San Bernardino
NCT05310838
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the First Episode Psychosis Trial Landscape
9 indexed First Episode Psychosis studies · 7 recruiting (78%).
Phase mix: 2 late (III/IV) vs 1 early (I/II).
Top sponsor: Northwell Health (3 trials), 5 others listed. 9 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for First Episode Psychosis?
PlainTrial tracks 9 US clinical trials for First Episode Psychosis, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for First Episode Psychosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.