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NCT06774430 · ClinicalTrials.gov registry record

Digital Strategies to Advance Help-Seeking Aim 1 and 2

A clinical trial of First Episode Psychosis and Clinical High-Risk, sponsored by Columbia University.

Recruiting
Registry status
25,000
Enrollment target
1
Study location

NCT06774430: Recruiting study of First Episode Psychosis and Clinical High-Risk, sponsored by Columbia University.

NCT06774430 is a study of First Episode Psychosis and Clinical High-Risk that is actively recruiting participants, run by Columbia University. The registered enrollment target is 25,000 participants, above the 3,308-participant average among 8 other First Episode Psychosis trials with a reported enrollment target (656% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06774430, a study of First Episode Psychosis and Clinical High-Risk, is actively recruiting participants, sponsored by Columbia University.

RECRUITING
Registry status
25,000 participants
Enrollment target
1
Study location

Study Summary

This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeking subtypes in 25,000 youth who screen positive for psychosis-risk on Mental Health America's national online screening platform, iteratively develop and test theory and data-driven, personalized strategies to advance help-seeking using Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial, identify the most accurate CHR screening threshold in an online environment, and link youth, when indicated, to local clinical care via Accelerating Medicines Partnership - Schizophrenia (AMP-SCZ), a NIH funded national network of CHR programs throughout the US. This academic-industry partnership aims to curate one of the largest datasets of youth with CHR, and to develop effective strategies to enhance early help-seeking, in a population where help-seeking is critical and a significant barrier to care.

Primary Outcome

Data from participants, including online metadata (time spent online, # of resources viewed, time spent to complete the PQ-B, # of texts initiated/exchanged), self-report (demographics, symptom type and severity, PQ-B score, goals/needs, self-efficacy), and natural language will be used to cluster participants into 4 categories: (1) Pre-intenders (take the PQ-B); (2) Intenders (initiate a text exchange with a peer navigator; (3) Actors (advance to clinical assessment); and (4) Super-actors (adva

Conditions Studied

First Episode Psychosis Clinical High-Risk Early Psychosis

Study Locations (1)

New York

  • Columbia University Irving Medical Center - New York

Trial Details

FieldValue
Enrollment Target 25,000 participants
Start Date 2025-04-07
Est. Completion 2028-05-31
Columbia University

958 total trials

What NCT06774430 shows while recruiting

NCT06774430 is an observational study that tracks outcomes without assigning an intervention. Its 25,000 participants enrollment target places it among the larger protocols in the corpus, above the 3,308-participant average among 8 other First Episode Psychosis trials with a reported enrollment target (656% higher).

The record links to 3 conditions, with First Episode Psychosis appearing as the primary indexed condition, and to 0 interventions.

NCT06774430 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT06774430 about?

NCT06774430 is a clinical study titled "Digital Strategies to Advance Help-Seeking Aim 1 and 2". This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeki...

What is the current status of trial NCT06774430?

This trial is currently recruiting. The enrollment target is 25,000 participants. The study started on 2025-04-07. Estimated completion is 2028-05-31.

What conditions does trial NCT06774430 study?

This clinical trial studies the following conditions: First Episode Psychosis, Clinical High-Risk, Early Psychosis.

Who is sponsoring clinical trial NCT06774430?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06774430 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for First Episode Psychosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06774430's enrollment target sits among peer trials

25,000 1st of 8 the highest of 8 other First Episode Psychosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other First Episode Psychosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06774430

Source: ClinicalTrials.gov NCT06774430, the US trial registry maintained by the National Library of Medicine. NCT06774430 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.