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ClinicalTrials.gov 5 recruiting now later-stage tilt small index

Fever: later-stage trial registry

5 of 19 indexed Fever trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 5 currently recruiting · #902 of 28,707 conditions by registered trial count

Fever: 19 US clinical trials tracked, 5 recruiting.

Fever is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Cumberland Pharmaceuticals, running 3 of these trials.

Enrollment posture brief

Registry condition fever

OPEN 5 | RECR 26% | LATE 8 | EARLY 1 | RANK #902 | SPON 3

Nearest open-share peer: Concussion, Mild (26% recruiting · 19 trials)

Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%Fever (this)26%
Open-enrollment share among volume-matched conditions near Fever

Fever lists 5 open slots (26% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Fever on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Fever is recruiting below its size-band peers.

    5 of 19 indexed trials (26.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Fever research.

    Cumberland Pharmaceuticals accounts for 3 of 19 trials (15.8%). 16 distinct sponsors appear on at least one study for this condition label.

  3. Typical Fever enrolment sits around 123 participants.

    Median target enrolment is 123 among the 19 trials that report a genuine target (sentinel values excluded). 7 of those (36.8%) plan for fewer than 100 participants.

  4. Fever splits between interventional and observational designs.

    13 interventional and 6 observational studies make up this index (68.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 33Phase 45

Open and recent trials

19 total, page 1 of 1

RECRUITING 5,000 participants

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

National Human Genome Research Institute (NHGRI)

NCT00001373

RECRUITING Phase 4 524 participants

Safety of RSV Preventive Monoclonal Antibody

Duke University

NCT07158814

RECRUITING NA 440 participants

Prescription Antipyretics to Decrease Unscheduled Return Visits In A Pediatric Emergency Department

University of Texas at Austin

NCT07074912

RECRUITING NA 300 participants

TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections

Inflammatix

NCT06637904

RECRUITING NA 150 participants

Remote Temperature Monitoring of Patients At Risk for Developing Fever

AION Biosystems

NCT06752512

ACTIVE NOT RECRUITING 1,000 participants

Tympanic Thermometer Study

Baxter Healthcare Corporation

NCT06556628

COMPLETED 2,084 participants

Clinical Evaluation of the FilmArray® Global Fever (GF) Panel

BioFire Defense

NCT02968355

COMPLETED 530 participants

FeverText: Assessing Fever Rates After Vaccination During the 2011-12 Influenza Season Using Text Messaging

Columbia University

NCT01467934

COMPLETED Phase 4 150 participants

Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen

Cumberland Pharmaceuticals

NCT01334944

COMPLETED Phase 3 123 participants

Efficacy, Safety, and Pharmacokinetics of Intravenous Ibuprofen in Adult Febrile Patients

Cumberland Pharmaceuticals

NCT01131000

COMPLETED Phase 3 118 participants

Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients

Cumberland Pharmaceuticals

NCT01002573

COMPLETED 105 participants

NC Thermometer (Gen 3) ISO 80601-2-56 Validation

Natural Cycles

NCT05721131

COMPLETED Phase 3 65 participants

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

National Cancer Institute (NCI)

NCT00001338

COMPLETED 60 participants

Comparison of Temporal to Pulmonary Artery Temperature Measurement in Patients With Fever

Massachusetts General Hospital

NCT01503294

COMPLETED Phase 4 60 participants

Ibuprofen Alone and in Combination With Acetaminophen for Treatment of Fever

Penn State University

NCT00267293

COMPLETED Phase 4 41 participants

Clinical Immunization Safety Assessment (CISA) Project: Pilot Study to Assess the Effect of Prophylactic Antipyretics on Immune Responses and Fever After IIV

Duke University

NCT01946594

COMPLETED Phase 4 20 participants

Temperature Control in Central Fever in the Neuro-ICU

Northwestern University

NCT00751634

COMPLETED NA 10 participants

Study of an App to Facilitate Communication With Parents of Febrile Infants

Yale University

NCT04328909

COMPLETED Phase 2 8 participants

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

M.D. Anderson Cancer Center

NCT02530515

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 3
Phase 4 5

Named interventions

Most-linked intervention names on Fever records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Ibuprofen Drug
2 trials
E-Care Device
1 trials
Intravenous ibuprofen Drug
1 trials
Gaymar Rapr-Round (external cooling blanket) Device
1 trials
FLAC chemotherapy with GM-CSF Drug
1 trials
Ex Vivo-activated Autologous Lymph Node Lymphocytes Biological
1 trials
NC° Thermometer (Gen 3) Device
1 trials
acetaminophen Drug
1 trials

US sites by state

Facility locations filed on Fever trials. A trial with sites in several states counts in each.

New York 7 trials
Texas 4 trials
North Carolina 4 trials
Georgia 4 trials
California 4 trials
Pennsylvania 3 trials
Maryland 3 trials
Florida 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Fever page

19 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Fever condition card totals 19 registered trials; most-linked intervention Ibuprofen; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.