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2026 data Public-data reference. official source

Fever

Open-data reference.

19 US clinical trials · 5 currently recruiting

Active & Recent Trials

RECRUITING 5,000 participants

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

National Human Genome Research Institute (NHGRI)

NCT00001373

RECRUITING Phase 4 524 participants

Safety of RSV Preventive Monoclonal Antibody

Duke University

NCT07158814

RECRUITING NA 440 participants

Prescription Antipyretics to Decrease Unscheduled Return Visits In A Pediatric Emergency Department

University of Texas at Austin

NCT07074912

RECRUITING NA 300 participants

TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections

Inflammatix

NCT06637904

RECRUITING NA 150 participants

Remote Temperature Monitoring of Patients At Risk for Developing Fever

AION Biosystems

NCT06752512

ACTIVE NOT RECRUITING 1,000 participants

Tympanic Thermometer Study

Baxter Healthcare Corporation

NCT06556628

COMPLETED 2,084 participants

Clinical Evaluation of the FilmArray® Global Fever (GF) Panel

BioFire Defense

NCT02968355

COMPLETED 530 participants

FeverText: Assessing Fever Rates After Vaccination During the 2011-12 Influenza Season Using Text Messaging

Columbia University

NCT01467934

COMPLETED Phase 4 150 participants

Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen

Cumberland Pharmaceuticals

NCT01334944

COMPLETED Phase 3 123 participants

Efficacy, Safety, and Pharmacokinetics of Intravenous Ibuprofen in Adult Febrile Patients

Cumberland Pharmaceuticals

NCT01131000

COMPLETED Phase 3 118 participants

Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients

Cumberland Pharmaceuticals

NCT01002573

COMPLETED 105 participants

NC Thermometer (Gen 3) ISO 80601-2-56 Validation

Natural Cycles

NCT05721131

COMPLETED Phase 3 65 participants

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

National Cancer Institute (NCI)

NCT00001338

COMPLETED 60 participants

Comparison of Temporal to Pulmonary Artery Temperature Measurement in Patients With Fever

Massachusetts General Hospital

NCT01503294

COMPLETED Phase 4 60 participants

Ibuprofen Alone and in Combination With Acetaminophen for Treatment of Fever

Penn State University

NCT00267293

COMPLETED Phase 4 41 participants

Clinical Immunization Safety Assessment (CISA) Project: Pilot Study to Assess the Effect of Prophylactic Antipyretics on Immune Responses and Fever After IIV

Duke University

NCT01946594

COMPLETED Phase 4 20 participants

Temperature Control in Central Fever in the Neuro-ICU

Northwestern University

NCT00751634

COMPLETED NA 10 participants

Study of an App to Facilitate Communication With Parents of Febrile Infants

Yale University

NCT04328909

COMPLETED Phase 2 8 participants

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

M.D. Anderson Cancer Center

NCT02530515

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 3
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Fever Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under Fever, and 5 of those are currently open to recruitment — roughly 26% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Fever shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Fever is led by Cumberland Pharmaceuticals with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Fever?

PlainTrial tracks 19 US clinical trials for Fever, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Fever?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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