Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
ER+ Breast Cancer: early-phase trial registry
7 of 9 indexed ER+ Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 7 currently recruiting · #1,916 of 28,707 conditions by registered trial count
ER+ Breast Cancer: 9 US clinical trials tracked, 7 recruiting.
ER+ Breast Cancer is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 2 of these trials.
Enrollment posture brief
Registry condition er-breast-cancer
OPEN 7 | RECR 78% | LATE 0 | EARLY 8 | RANK #1916 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Advanced Colorectal Carcinoma (78% recruiting · 9 trials)
ER+ Breast Cancer lists 7 open slots (78% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for ER+ Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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ER+ Breast Cancer is recruiting above its size-band peers.
7 of 9 indexed trials (77.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates ER+ Breast Cancer research.
Memorial Sloan Kettering Cancer Center accounts for 2 of 9 trials (22.2%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical ER+ Breast Cancer enrolment sits around 85 participants.
Median target enrolment is 85 among the 9 trials that report a genuine target (sentinel values excluded). 5 of those (55.6%) plan for fewer than 100 participants.
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ER+ Breast Cancer research is mostly interventional.
9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT07483307
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
858 Therapeutics
NCT06395519
Breast Re-irradiation After Second Ipsilateral Lumpectomy
Youssef Zeidan
NCT06867484
JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
Jacobio Pharmaceuticals Co.
NCT05490472
Circulating Tumor DNA
Yale University
NCT06923527
A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT05534438
FES Imaging to Optimize Tamoxifen for Metastatic Breast Cancer
University of Wisconsin, Madison
NCT04174352
Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications
Boundless Bio
NCT05827614
Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
RayzeBio
NCT06590857
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on ER+ Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on ER+ Breast Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this ER+ Breast Cancer page
9 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 ER+ Breast Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most ER+ Breast Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This ER+ Breast Cancer condition card totals 9 registered trials; most-linked intervention BBI-825; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.